Monoclonal antibodies binding data for SARS-CoV-2 proteins.
Data Brief
; 43: 108415, 2022 Aug.
Article
in English
| MEDLINE | ID: covidwho-1906939
ABSTRACT
SARS-CoV-2 pandemic opens up the curiosity of understanding the coronavirus. This demand for the development of the regent, which can be used for academic and therapeutic applications. The present data provide the biochemical characterization of synthetically developed monoclonal antibodies for the SARS-CoV-2 proteins. The antibodies from phage-displayed antibody libraries were selected with the SARS-CoV-2 proteins immobilized in microwell plates. The clones which bind to the antigen in Fab-phage ELISA were selected, and a two-point competitive phage ELISA was performed. Antibodies binding kinetic of IgGs for SARS-CoV2 proteins further carried with B.L.I. Systematic analysis of binding with different control proteins and purified SARS-CoV-2 ensured the robustness of the antibodies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Systematic review/Meta Analysis
Language:
English
Journal:
Data Brief
Year:
2022
Document Type:
Article
Affiliation country:
J.dib.2022.108415
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