Your browser doesn't support javascript.
Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records.
Thompson, Ellen J; Williams, Dylan M; Walker, Alex J; Mitchell, Ruth E; Niedzwiedz, Claire L; Yang, Tiffany C; Huggins, Charlotte F; Kwong, Alex S F; Silverwood, Richard J; Di Gessa, Giorgio; Bowyer, Ruth C E; Northstone, Kate; Hou, Bo; Green, Michael J; Dodgeon, Brian; Doores, Katie J; Duncan, Emma L; Williams, Frances M K; Steptoe, Andrew; Porteous, David J; McEachan, Rosemary R C; Tomlinson, Laurie; Goldacre, Ben; Patalay, Praveetha; Ploubidis, George B; Katikireddi, Srinivasa Vittal; Tilling, Kate; Rentsch, Christopher T; Timpson, Nicholas J; Chaturvedi, Nishi; Steves, Claire J.
  • Thompson EJ; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK. ellen.thompson@kcl.ac.uk.
  • Williams DM; MRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK. dylan.williams@ucl.ac.uk.
  • Walker AJ; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. dylan.williams@ucl.ac.uk.
  • Mitchell RE; Bennett Institute for Applied Data Science, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxfort, UK.
  • Niedzwiedz CL; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Yang TC; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Huggins CF; Institute of Health & Wellbeing, University of Glasgow, Glasgow, UK.
  • Kwong ASF; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, BD9 6RJ, UK.
  • Silverwood RJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Di Gessa G; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Bowyer RCE; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.
  • Northstone K; Centre for Longitudinal Studies, UCL Social Research Institute, University College London, London, UK.
  • Hou B; Department of Epidemiology and Public Health, University College London, London, UK.
  • Green MJ; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.
  • Dodgeon B; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
  • Doores KJ; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, BD9 6RJ, UK.
  • Duncan EL; MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
  • Williams FMK; Centre for Longitudinal Studies, UCL Social Research Institute, University College London, London, UK.
  • Steptoe A; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.
  • Porteous DJ; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.
  • Tomlinson L; Department of Epidemiology and Public Health, University College London, London, UK.
  • Goldacre B; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK.
  • Patalay P; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, BD9 6RJ, UK.
  • Ploubidis GB; Electronic Health Records Research Group, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
  • Katikireddi SV; Bennett Institute for Applied Data Science, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxfort, UK.
  • Tilling K; MRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.
  • Rentsch CT; Centre for Longitudinal Studies, UCL Social Research Institute, University College London, London, UK.
  • Timpson NJ; Centre for Longitudinal Studies, UCL Social Research Institute, University College London, London, UK.
  • Chaturvedi N; MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
  • Steves CJ; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
Nat Commun ; 13(1): 3528, 2022 06 28.
Article in English | MEDLINE | ID: covidwho-1908168
ABSTRACT
The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden and possible causes of long COVID in the community, we coordinated analyses of survey data from 6907 individuals with self-reported COVID-19 from 10 UK longitudinal study (LS) samples and 1.1 million individuals with COVID-19 diagnostic codes in electronic healthcare records (EHR) collected by spring 2021. Proportions of presumed COVID-19 cases in LS reporting any symptoms for 12+ weeks ranged from 7.8% and 17% (with 1.2 to 4.8% reporting debilitating symptoms). Increasing age, female sex, white ethnicity, poor pre-pandemic general and mental health, overweight/obesity, and asthma were associated with prolonged symptoms in both LS and EHR data, but findings for other factors, such as cardio-metabolic parameters, were inconclusive.
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Electronic Health Records / COVID-19 Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Female / Humans Country/Region as subject: Europa Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2022 Document Type: Article Affiliation country: S41467-022-30836-0

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Electronic Health Records / COVID-19 Type of study: Cohort study / Observational study / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Female / Humans Country/Region as subject: Europa Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2022 Document Type: Article Affiliation country: S41467-022-30836-0