Revisiting the potential role of BCG and MMR vaccines in COVID-19.
Sci Prog
; 105(2): 368504221105172, 2022.
Article
in English
| MEDLINE | ID: covidwho-1909995
ABSTRACT
Despite the development and deployment of effective COVID-19 vaccines, many regions remain poorly covered. Seeking alternative tools for achieving immunity against COVID-19 remains to be of high importance. "Trained immunity" is the nonspecific immune response usually established through administering live attenuated vaccines and is a potential preventive tool against unrelated infections. Evidence regarding a possible protective role for certain live attenuated vaccines against COVID-19 has emerged mainly for those administered as part of childhood vaccination protocols. This review summarizes the relevant literature about the potential impact of Bacille Calmette-Guérin (BCG) and measles, mumps and rubella (MMR) vaccines on COVID-19. Existing available data suggest a potential role for BCG and MMR in reducing COVID-19 casualties and burden. However, more investigation and comparative studies are required for a better understanding of their impact on COVID-19 outcomes.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Rubella
/
COVID-19
/
Mumps
Type of study:
Observational study
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Sci Prog
Year:
2022
Document Type:
Article
Affiliation country:
00368504221105172
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