Your browser doesn't support javascript.
SARS-CoV-2 antibody prevalence among homeless people and shelter workers in Denmark: a nationwide cross-sectional study.
Eriksen, Alexandra R Röthlin; Fogh, Kamille; Hasselbalch, Rasmus B; Bundgaard, Henning; Nielsen, Susanne D; Jørgensen, Charlotte S; Scharff, Bibi F S S; Erikstrup, Christian; Sækmose, Susanne G; Holm, Dorte K; Aagaard, Bitten; Kristensen, Jonas H; Bødker, Cecilie A; Norsk, Jakob B; Nielsen, Pernille B; Østergaard, Lars; Ellermann-Eriksen, Svend; Andersen, Berit; Nielsen, Henrik; Johansen, Isik S; Wiese, Lothar; Simonsen, Lone; K Fischer, Thea; Folke, Fredrik; Lippert, Freddy; Ostrowski, Sisse R; Ethelberg, Steen; Koch, Anders; Vangsted, Anne-Marie; Krause, Tyra; Fomsgaard, Anders; Nielsen, Claus; Ullum, Henrik; Skov, Robert; Iversen, Kasper.
  • Eriksen ARR; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark. alexandra.rosengaard.roethlin.eriksen.01@regionh.dk.
  • Fogh K; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark. alexandra.rosengaard.roethlin.eriksen.01@regionh.dk.
  • Hasselbalch RB; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. alexandra.rosengaard.roethlin.eriksen.01@regionh.dk.
  • Bundgaard H; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Nielsen SD; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Jørgensen CS; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Scharff BFSS; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Erikstrup C; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Sækmose SG; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Holm DK; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Aagaard B; Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • Kristensen JH; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Bødker CA; Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • Norsk JB; Statens Serum Institut, Copenhagen, Denmark.
  • Nielsen PB; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Østergaard L; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
  • Ellermann-Eriksen S; Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
  • Andersen B; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Nielsen H; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Johansen IS; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark.
  • Wiese L; Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
  • Simonsen L; Department of Research Medicine, University of Southern Denmark, Odense, Denmark.
  • K Fischer T; Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
  • Folke F; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Lippert F; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Ostrowski SR; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Ethelberg S; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Koch A; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Vangsted AM; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Krause T; Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
  • Fomsgaard A; Department of Emergency Medicine, Copenhagen University Hospital, Herlev and Gentofte, Herlev, Denmark.
  • Nielsen C; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
  • Ullum H; Department of Clinical Microbiology, Aarhus University Hospital, Aarhus, Denmark.
  • Skov R; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Iversen K; University Research Clinic for Cancer Screening, Randers Regional Hospital, Randers, Denmark.
BMC Public Health ; 22(1): 1261, 2022 06 27.
Article in English | MEDLINE | ID: covidwho-1910302
ABSTRACT

BACKGROUND:

People experiencing homelessness (PEH) and associated shelter workers may be at higher risk of infection with "Severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2). The aim of this study was to determine the prevalence of SARS-CoV-2 among PEH and shelter workers in Denmark. DESIGN AND

METHODS:

In November 2020, we conducted a nationwide cross-sectional seroprevalence study among PEH and shelter workers at 21 recruitment sites in Denmark. The assessment included a point-of-care test for antibodies against SARS-CoV-2, followed by a questionnaire. The seroprevalence was compared to that of geographically matched blood donors considered as a proxy for the background population, tested using a total Ig ELISA assay.

RESULTS:

We included 827 participants in the study, of whom 819 provided their SARS-CoV-2 antibody results. Of those, 628 were PEH (median age 50.8 (IQR 40.9-59.1) years, 35.5% female) and 191 were shelter workers (median age 46.6 (IQR 36.1-55.0) years and 74.5% female). The overall seroprevalence was 6.7% and was similar among PEH and shelter workers (6.8% vs 6.3%, p = 0.87); and 12.2% among all participants who engaged in sex work. The overall participant seroprevalence was significantly higher than that of the background population (2.9%, p < 0.001). When combining all participants who reported sex work or were recruited at designated safe havens, we found a significantly increased risk of seropositivity compared to other participants (OR 2.23, 95%CI 1.06-4.43, p = 0.02). Seropositive and seronegative participants reported a similar presence of at least one SARS-CoV-2 associated symptom (49% and 54%, respectively). INTERPRETATIONS The prevalence of SARS-CoV-2 antibodies was more than twice as high among PEH and associated shelter workers, compared to the background population. These results could be taken into consideration when deciding in which phase PEH are eligible for a vaccine, as part of the Danish national SARS-CoV-2 vaccination program rollout.

FUNDING:

TrygFonden and HelseFonden.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Ill-Housed Persons / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: BMC Public Health Journal subject: Public Health Year: 2022 Document Type: Article Affiliation country: S12889-022-13642-7

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Ill-Housed Persons / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Topics: Vaccines Limits: Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: BMC Public Health Journal subject: Public Health Year: 2022 Document Type: Article Affiliation country: S12889-022-13642-7