A rare case of cardiomyopaty: a case report
Italian Journal of Medicine
; 16(SUPPL 1):79, 2022.
Article
in English
| EMBASE | ID: covidwho-1912978
ABSTRACT
A 46-years old Egyptian man was admitted to our department because of the onset of worsening dyspnea. In his clinical history were present hypothyroidism, obesity, hyperuricemia, hypertension and recent Sars-Cov2 infection. Bilateral pleuric effusion was suspected during physical examination and confirmed by chest CT. Blood data showed mild macrocytic anemia, increased levels of creatinine, transaminases, pro-BNP (3574 pg/ml cut-off 0-125) and D-dimer. Multiple molecular swabs for research of Sars-Cov2 were negative. ECG showed sinus rhythm and non specific atypia of repolarization. An eco-fast was performed at bedside and revelead left ventricular dilatation and severe systolic disfunction due to diffuse hypokinesia (EF 30%). Diuretic therapy was set up with improvement of the clinical status. In order to exclude ischaemic genesis of the cardiopathy a coronary angiography was performed without evidence of obstructive lesions. An echocardiogram was repeated and it showed a parietal ipertrabeculation of the left ventricle. This aspect was suggestive of non-compact myocardium, a rare disease due to the arrest of the myocardial maturation process during fetal development, leading to the persistence of embryonic structures in the heart muscle. Genetic inheritance arises in 30-50% of patients and are involved genes that generally seem to encode sarcomeric or cytoskeletal proteins.Cardiac MRI is planned in order to have further confirmation of our diagnostic hypothesis. In the meantime wearable defibrillator was prescribed for the prevention of sudden death.
aminotransferase; creatinine; cytoskeleton protein; D dimer; endogenous compound; adult; cardiac muscle; cardiovascular magnetic resonance; case report; clinical article; conference abstract; coronary angiography; coronavirus disease 2019; cytoskeleton; defibrillator; dilatation; diuretic therapy; dyspnea; echocardiography; Egyptian; electrocardiogram; electrocardiography; embryo; embryonic structures; fetus development; heart left ventricle; human; hypertension; hyperuricemia; hypokinesia; hypothyroidism; inheritance; macrocytic anemia; male; middle aged; nonhuman; obesity; physical examination; pleura; prevention; rare disease; repolarization; sarcomere; Severe acute respiratory syndrome coronavirus 2; sinus rhythm; sudden death; systolic dysfunction; thorax
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Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Case report
Language:
English
Journal:
Italian Journal of Medicine
Year:
2022
Document Type:
Article
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