Transplanting thoracic COVID-19 positive donors: An institutional protocol and report of the first 14 cases.
J Heart Lung Transplant
; 41(10): 1376-1381, 2022 10.
Article
in English
| MEDLINE | ID: covidwho-1914428
ABSTRACT
We present our institution's protocol for evaluating and transplanting thoracic organs from COVID-19 positive donors and report the outcomes to date. Hearts from donors testing positive for COVID-19 on any test were eligible for transplantation at our institution provided the donor exhibited no evidence of hypercoagulability or COVID-19 induced hyperinflammatory state during terminal hospitalization. Lungs were eligible if the donor first tested PCR positive on nasopharyngeal swab (NPS) for COVID-19 > 20 days prior to procurement and had a negative lower respiratory tract specimen. We performed 14 thoracic transplants in 13 recipients using organs from COVID-19 positive donors. None of the recipients or healthcare members acquired COVID-19. No recipients suffered unexpected acute rejection. Patient survival is 92% to date, with graft survival 93%. The use of hearts from COVID-19 positive donors may be safe and effective. Transplantation of lungs is unresolved but may be cautiously pursued under the restricted circumstances.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tissue and Organ Procurement
/
Lung Transplantation
/
COVID-19
Type of study:
Experimental Studies
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
J Heart Lung Transplant
Journal subject:
Cardiology
/
Transplantation
Year:
2022
Document Type:
Article
Affiliation country:
J.healun.2022.06.018
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