Filtration efficiency of N95 filtering facepiece respirators during multi-cycles of '8-hour simulated donning + disinfection'.
J Hosp Infect
; 127: 91-100, 2022 Sep.
Article
in English
| MEDLINE | ID: covidwho-1914598
ABSTRACT
BACKGROUND:
Aerosol-borne diseases such as COVID-19 may outbreak occasionally in various regions of the world, inevitably resulting in short-term shortage and corresponding reuse of disposable respirators.AIM:
To investigate the effective disinfection methods, reusable duration and frequency of N95 respirators.METHODS:
Based on the self-built respirator simulation test system, and under combinations of experimental conditions of three N95 respirators × 0-200 nm NaCl aerosols × three simulated breathing flow rates (15, 50 and 85 L/min) × two disinfection methods (dry heating and ultraviolet (UV) radiation), this study continuously measured the changes in filtration efficiency of all respirators during multi-cycles of '8-h simulated donning + disinfection' until the penetration reached ≥5%.FINDINGS:
Multi-cycles of dry heating and UV radiation treatments on the reused (i.e., multiple 8-h donning) N95 respirators had a minimal effect (<0.5%) on the respirator filtration efficiency, and even at 85 L/min, all tested N95 respirators were able to maintain filtration efficiencies ≥95% for at least 30 h or four reuse cycles of '8-h donning + disinfection', while a lower breathing flow rate (15 L/min) plus the exhalation valve could further extend the N95 respirator's usability duration up to 140 h or 18 reuse cycles of '8-h donning + disinfection'. As the respirator wearing time extended, aerosol penetration slowly increased in a quadratic function with a negative second-order coefficient, and the penetration increment during each cycle of 8-h donning was less than 0.9%.CONCLUSION:
Multi-cycles of N95 respirator reuse in combination with dry heating or UV irradiation disinfection are feasible.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiratory Protective Devices
/
COVID-19
Limits:
Humans
Language:
English
Journal:
J Hosp Infect
Year:
2022
Document Type:
Article
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