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Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022.
de Kleine, Ruben H; Lexmond, Willem S; Buescher, Gustav; Sturm, Ekkehard; Kelly, Deidre; Lohse, Ansgar W; Lenz, Dominic; Hørby Jørgensen, Marianne.
  • de Kleine RH; Department of Surgery, Division of Hepatobiliairy Surgery and Liver Transplantation, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
  • Lexmond WS; European Reference Network for hepatological diseases (ERN RARE-LIVER).
  • Buescher G; European Reference Network for hepatological diseases (ERN RARE-LIVER).
  • Sturm E; Department of Paediatrics, Division of Gastroenterology and Hepatology, Beatrix Children's Hospital, University of Groningen, Groningen, The Netherlands.
  • Kelly D; European Reference Network for hepatological diseases (ERN RARE-LIVER).
  • Lohse AW; Department of Internal Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Lenz D; European Reference Network for hepatological diseases (ERN RARE-LIVER).
  • Hørby Jørgensen M; Paediatric Gastroenterology/ Hepatology, University Hospital Tuebingen, Tuebingen, Germany.
Euro Surveill ; 27(19)2022 05.
Article in English | MEDLINE | ID: covidwho-1917174
ABSTRACT
To detect potential concern about severe acute hepatitis in children, we conducted a survey among 50 ERN RARE-LIVER centres. By 26 April 2022, 34 centres, including 25 transplant centres, reported an estimated median of 3-5, 0-2 and 3-5 cases in 2021, 2020 and 2019 and a mean of 2 (range 0-8) cases between January and April 2022 (mean in 10 large liver transplant centres 3). Twelve centres reported suspicion of an increase, but no rise.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Liver Transplantation / Liver Failure, Acute / Hepatitis Type of study: Diagnostic study / Observational study / Randomized controlled trials Limits: Child / Humans Country/Region as subject: Asia Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: 1560-7917.ES.2022.27.19.2200369

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Liver Transplantation / Liver Failure, Acute / Hepatitis Type of study: Diagnostic study / Observational study / Randomized controlled trials Limits: Child / Humans Country/Region as subject: Asia Language: English Journal subject: Communicable Diseases Year: 2022 Document Type: Article Affiliation country: 1560-7917.ES.2022.27.19.2200369