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De Novo-Whole Genome Assembly of the Roborovski Dwarf Hamster (Phodopus roborovskii) Genome: An Animal Model for Severe/Critical COVID-19.
Andreotti, Sandro; Altmüller, Janine; Quedenau, Claudia; Borodina, Tatiana; Nouailles, Geraldine; Teixeira Alves, Luiz Gustavo; Landthaler, Markus; Bieniara, Maximilian; Trimpert, Jakob; Wyler, Emanuel.
  • Andreotti S; Department of Mathematics and Computer Science, Institute of Computer Science, Freie Universität Berlin, Takustr. 9, Berlin, Germany.
  • Altmüller J; Cologne Center for Genomics, University of Cologne, Cologne, Germany.
  • Quedenau C; Scientific Genomics Platforms, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Borodina T; Scientific Genomics Platforms, Max Delbrück Center for Molecular Medicine, Berlin, Germany.
  • Nouailles G; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
  • Teixeira Alves LG; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology, Berlin, Germany.
  • Landthaler M; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology, Berlin, Germany.
  • Bieniara M; IRI Life Sciences, Institute of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.
  • Trimpert J; Department of Mathematics and Computer Science, Institute of Computer Science, Freie Universität Berlin, Takustr. 9, Berlin, Germany.
  • Wyler E; Institut für Virologie, Freie Universität Berlin, Berlin, Germany.
Genome Biol Evol ; 14(7)2022 07 02.
Article in English | MEDLINE | ID: covidwho-1922238
ABSTRACT
The Roborovski dwarf hamster Phodopus roborovskii belongs to the Phodopus genus, one of the seven within Cricetinae subfamily. Like other rodents such as mice, rats, or ferrets, hamsters can be important animal models for a range of diseases. Whereas the Syrian hamster from the genus Mesocricetus is now widely used as a model for mild-to-moderate coronavirus disease 2019, Roborovski dwarf hamster shows a severe-to-lethal course of disease upon infection with the novel human coronavirus severe acute respiratory syndrome coronavirus 2.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Phodopus / COVID-19 Type of study: Prognostic study Limits: Animals / Humans Language: English Journal subject: Biology / Molecular Biology Year: 2022 Document Type: Article Affiliation country: Gbe

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Phodopus / COVID-19 Type of study: Prognostic study Limits: Animals / Humans Language: English Journal subject: Biology / Molecular Biology Year: 2022 Document Type: Article Affiliation country: Gbe