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Medication-resistant acute focal motor seizures in a child with COVID-19 affecting the CNS
Sadeghian, Saeid; Momen, Aliakbar; Jelodar, Gholamreza; Nasiri, Shahram; Azizimalamiri, Reza.
  • Sadeghian S; Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  • Momen A; Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  • Jelodar G; Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  • Nasiri S; Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
  • Azizimalamiri R; Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Epileptic Disord ; 24(5): 941-946, 2022 10 01.
Article in English | MEDLINE | ID: covidwho-1923779
ABSTRACT
A perfectly healthy preschool girl presented with acute repetitive focal aware motor seizures, while her brain MRI showed a lesion in the left posterior cortex. After a number of investigations, her cerebrospinal fluid PCR was positive for SARS-CoV-2. Despite receiving at least four anti-seizure medications at appropriate dosages, the seizures continued, and just after administering intravenous immunoglobulin, her seizures stopped. This dramatic response to intravenous immunoglobulin may indicate a hypothetical inflammatory process in the patient's cortex caused by COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epilepsy, Partial, Motor / COVID-19 Topics: Long Covid Limits: Child / Child, preschool / Female / Humans Language: English Journal: Epileptic Disord Journal subject: Brain / Neurology Year: 2022 Document Type: Article Affiliation country: Epd.2022.1461

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Epilepsy, Partial, Motor / COVID-19 Topics: Long Covid Limits: Child / Child, preschool / Female / Humans Language: English Journal: Epileptic Disord Journal subject: Brain / Neurology Year: 2022 Document Type: Article Affiliation country: Epd.2022.1461