[Progress in the study of antiviral activity of cepharanthine against SARS-CoV-2].
Nan Fang Yi Ke Da Xue Xue Bao
; 42(6): 955-956, 2022 Jun 20.
Article
in Chinese
| MEDLINE | ID: covidwho-1924684
ABSTRACT
As a member of the dibenzyl isoquinoline alkaloid family, cepharathine is an alkaloid from the traditional Chinese medicine cepharathine, which is mainly used for treatment of leukopenia and other diseases. Recent studies of the inhibitory effect of cepharathine against SARS-CoV-2 have attracted widespread attention and aroused heated discussion. As the original discoverer of the anti-SARS-CoV-2 activity of cepharanthine, here we briefly summarize the discovery of cepharanthine and review important progress in relevant studies concerning the discovery and validation of anti-SARS-CoV-2 activity of cepharathine, its antiviral mechanisms and clinical trials of its applications in COVID-19 therapy.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Benzylisoquinolines
/
COVID-19
Type of study:
Prognostic study
Topics:
Traditional medicine
Limits:
Humans
Language:
Chinese
Journal:
Nan Fang Yi Ke Da Xue Xue Bao
Year:
2022
Document Type:
Article
Affiliation country:
J.issn.1673-4254.2022.06.22
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