Comparison between COVID19 outcomes in the first 3 waves of the pandemic: a reference hospital report.
Pol Arch Intern Med
; 132(10)2022 10 21.
Article
in English
| MEDLINE | ID: covidwho-2091285
ABSTRACT
INTRODUCTION:
The course of consecutive COVID19 waves was influenced by medical and organizational factors.OBJECTIVES:
We aimed to assess the outcomes of patients hospitalized for COVID19 during the first 3 waves of the pandemic. PATIENTS ANDMETHODS:
We performed a retrospective analysis of medical records of all COVID19 patients admitted to the University Hospital in Kraków, Poland, a designated COVID19 hospital in Malopolska province, between March 1, 2020 and May 31, 2021. The waves were defined as 1, 2, and 3, and covered the periods of March 2020 to July 2020, August 2020 to January 2021, and February 2021 to May 2021, respectively. Patients' characteristics and outcomes for waves 1 through 3 were compared.RESULTS:
Data analyses included 5191 patients with COVID19. We found differences in age (mean [SD], 60.2 [17.3] years vs 62.4 [16.8] years vs 61.9 [16.1] years, respectively, for waves 1, 2, and 3; P = 0.003), sex distribution (proportion of women, 51.4% vs 44.2% vs 43.6%; P = 0.003), as well as concentrations of inflammatory markers and oxygen saturation (the lowest and the highest for wave 1, respectively; P <0.001). Hospital death rates in subsequent waves were 10.4%, 19.8%, and 20.3% (P <0.001). Despite similarities in patients' characteristics, the length of hospital and intensive care unit stay was shorter for wave 3 than for wave 2. The risk factors for inhospital death were advanced age, male sex, cardiovascular or chronic kidney disease, higher Creactive protein level, and hospitalization during the second or third wave.CONCLUSIONS:
We identified differences in patients' clinical characteristics and outcomes between consecutive pandemic waves, which probably reflect changes in terms of COVID19 isolation policy, hospitalization and treatment indications, and treatment strategies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pandemics
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Pamw.16286
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