Immunopatogenetic basis of the severity of COVID-19. Literature review

Yessenbayeva, A. A.; Mussazhanova, Z. B.; Kazymov, M. S.; Apsalikov, B. A.; Dastan, N. S.; Shalgumbayeva, G. M.; Kozykenova, Z. U.; Krykpayeva, A. S.; Khamitova, M. O.; Massabayeva, M. R.

Yessenbayeva, A. A.; Mussazhanova, Z. B.; Kazymov, M. S.; Apsalikov, B. A.; Dastan, N. S.; Shalgumbayeva, G. M.; Kozykenova, Z. U.; Krykpayeva, A. S.; Khamitova, M. O.; Massabayeva, M. R..

Science & Healthcare ; 24(2):93-102, 2022.

Article in English | GIM | ID: covidwho-1924995

ABSTRACT

ABSTRACT

Relevance. The outbreak of COVID-19 began in late 2019 in Hubei Province, China. Already in the first quarter of 2020, the disease spread around the world. On March 11, 2020, the WHO declared a COVID-19 pandemic. The first cases of the disease in Kazakhstan were registered in March 2020. The aim of the study a systematic search for scientific information about the socially significant disease COVID-19 and its immunopathogenetic basis for the severity of the course. Search strategy Research publications were searched in PubMed, ResearchGate, GoogleScholar databases. A total of 325 references were found, of which 89 were selected for analysis.

Keywords

human diseases; coronavirus disease 2019; viral diseases; pandemics; immunopathogenesis; disease course; literature reviews; outbreaks; systematic reviews; data collection; clinical aspects; asymptomatic infections; epidemiology; survival; cytokines; inflammation; immune response; severe course; causes of death; mortality; immune system; systemic inflammatory response syndrome; acute respiratory distress syndrome; lungs; respiratory diseases; blood coagulation disorders; thrombosis; prognosis; complications; leukocytes; immunological markers; acute course; man; Severe acute respiratory syndrome coronavirus 2; blood disease bacterium; Kazakhstan; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Central Asia; Asia; upper-middle income countries; very high Human Development Index countries; West Asia; Ralstonia; Burkholderiaceae; Burkholderiales; Betaproteobacteria; Proteobacteria; Bacteria; prokaryotes; SARS-CoV-2; viral infections; disease progression; data logging; clinical picture; immunity reactions; immunological reactions; death rate; Sirs; lung diseases; blood clots; leucocytes; white blood cells; immunochemical markers

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Full text: Available Collection: Databases of international organizations Database: GIM Type of study: Prognostic study / Reviews Language: English Journal: Science & Healthcare Year: 2022 Document Type: Article

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