Characteristics and Outcomes Associated With COVID-19 Infection in Pregnancy
Obstetrics and Gynecology
; 139(SUPPL 1):55S, 2022.
Article
in English
| EMBASE | ID: covidwho-1925529
ABSTRACT
INTRODUCTION:
Data on COVID-19 in pregnancy are skewed toward infection at time of labor and delivery, and few studies have controlled for confounding variables. We aimed to explore the sociodemographic and health risk factors for COVID-19 at any point in pregnancy and its impact on maternal outcomes in a diverse cohort during the first year of the pandemic.METHODS:
We conducted a retrospective cohort study using data ed from the electronic medical record within Kaiser Permanente Mid-Atlantic States, an integrated health care system, from March 15, 2020, to March 15, 2021. We included women at least 15 years old and pregnant during that timeframe, comparing those who tested positive for COVID-19 to those who did not.We usedmultivariable logistic regression to identify risk factors for COVID-19 infection during pregnancy.We then used propensity score matching to create a comparison group to explore associations between infection and key outcomes.RESULTS:
Among 18,285 pregnant members, 1,036 (5.7%) tested positive for COVID-19 during pregnancy, with 26%, 31%, and 43%, respectively, diagnosed in each trimester of pregnancy. Patients with COVID-19 were more likely to be young, Latina, obese, and multiparous;being White or Asian was protective (P<.001). Patients with COVID-19 during pregnancy were more likely to be hospitalized apart from delivery (P=.029). There were no significant differences in fetal demise, cesarean delivery, preterm delivery, gestational diabetes, hypertensive disorders of pregnancy, venous thromboembolism, postpartum readmission, or maternal death between groups.CONCLUSION:
Our study was consistent with previously identified disparities in COVID-19 infection. Outcome data were surprisingly reassuring.
adult; cesarean section; cohort analysis; complication; conference abstract; controlled study; coronavirus disease 2019; demography; electronic medical record; female; fetus death; health hazard; hospital readmission; human; integrated health care system; maternal death; maternal hypertension; multipara; obesity; obstetric delivery; outcome assessment; pandemic; pregnancy; pregnancy complication; pregnancy diabetes mellitus; prematurity; propensity score; retrospective study; risk factor; venous thromboembolism
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Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
Obstetrics and Gynecology
Year:
2022
Document Type:
Article
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