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Clinical presentations of adult and pediatric SARS-CoV-2-positive cases in a community cohort, Nashville, Tennessee.
Rankin, Danielle A; Yanis, Ahmad; Talj, Rana; Howe, Harrison L; Bloos, Sean M; Fernandez, Kailee N; Amarin, Justin Z; Bruce, Mercedes; Salib, Seifein; Hargrave, Samarian; Chappell, James D; Spieker, Andrew J; Halasa, Natasha B; Howard, Leigh M.
  • Rankin DA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Yanis A; Vanderbilt Epidemiology PhD Program, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
  • Talj R; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Howe HL; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Bloos SM; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Fernandez KN; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Amarin JZ; Tulane University School of Medicine, Tulane University, New Orleans, Louisiana, USA.
  • Bruce M; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Salib S; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Hargrave S; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Chappell JD; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Spieker AJ; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Halasa NB; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Howard LM; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
J Med Virol ; 94(11): 5560-5566, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-1925949
ABSTRACT
Compared to adults, the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) illness in children has been lower and less severe. However, reports comparing SARS-CoV-2 infection among children and adults are limited. As part of our longitudinal cohort study of adults and children with SARS-CoV-2 infection and their household contacts in Nashville, Tennessee, we compared the clinical characteristics and outcomes of SARS-CoV-2 infections between children and adults. Children were more likely to be asymptomatically infected and had a shorter illness duration compared to adults. The differences observed in clinical presentation across ages may inform symptom-specific testing, screening, and management algorithms.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Limits: Adult / Child / Humans Country/Region as subject: North America Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27988

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Limits: Adult / Child / Humans Country/Region as subject: North America Language: English Journal: J Med Virol Year: 2022 Document Type: Article Affiliation country: Jmv.27988