THE IMPACT OF SARS-COV-2 INFECTION ON THE OUTCOME OF ACUTE ISCHEMIC STROKE - A RETROSPECTIVE COHORT STUDY
European Stroke Journal
; 7(1 SUPPL):462, 2022.
Article
in English
| EMBASE | ID: covidwho-1928134
ABSTRACT
Background:
Acute ischemic stroke (AIS) is a frequent complication of coronavirus disease (COVID-19), but the prognosis of these patients is poorly understood.Aim:
To explore the impact of COVID-19 on neurological outcome in AIS patients.Methods:
A comparative retrospective cohort study was conducted in 32 consecutive AIS patients with and 51 without COVID-19 between the 1st of March 2020 and 1st of May 2021. The evaluation was based on a detailed chart review for demographic data, medical history, stroke severity, cranial and vessel imaging results, laboratory parameters, COVID-19 severity, hospitalization time, in-hospital mortality, and functional deficits at discharge (modified Rankin Scale, mRS).Results:
COVID-19 AIS patients had worse initial neurological deficit (NIHSS 9 (3-13) vs. 4 (2-10);p=0.06), showed tendency to higher rate of large vessel occlusion (LVO;13/32 vs. 14/51;p=0.21), had prolonged hospitalization (19.4 ± 17.7 vs. 9.7 ± 7 days;p=0.003), had lower chance of functional independence (mRS≤2) (12/32 vs. 32/51;p=0.02) and showed higher in-hospital mortality (10/32 vs. 6/51;p=0.02). In COVID-19 AIS patients, LVO was more common with COVID-19 pneumonia than without (55.6% vs. 23.1%;p=0.139).Conclusion:
COVID-19-related AIS carries a worse prognosis. COVID- 19 with pneumonia seems to be associated with a higher rate of LVO.
acute ischemic stroke; adult; blood vessel occlusion; cerebrovascular accident; clinical article; cohort analysis; conference abstract; controlled study; coronavirus disease 2019; demographics; female; hospitalization; human; in-hospital mortality; male; medical history; medical record review; National Institutes of Health Stroke Scale; neurologic disease; outcome assessment; prognosis; Rankin scale; retrospective study; stroke patient
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
Language:
English
Journal:
European Stroke Journal
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS