Coronavirus Disease-19 associated arthritis-An observational study
Indian Journal of Rheumatology
; 17(2):153-156, 2022.
Article
in English
| EMBASE | ID: covidwho-1928755
ABSTRACT
Background:
The coronavirus disease or COVID-19 pandemic is the major global health crisis of the present time. Various rheumatological manifestations have been reported during or after COVID-19 infection, but data are scarce. In this observational study, we have tried to analyze the clinical characteristics of COVID-19 associated arthralgia/arthritis.Methods:
We have collected the clinical data of 14 patients over the past 6 months who have developed arthralgia or arthritis during or after symptomatic COVID-19 infection, proven by a positive reverse transcription-polymerase chain reaction test from nasopharyngeal swab.Results:
The most common symptoms during COVID-19 infection in the 14 patients were fever and myalgia, being present in 92.8% and 64.3% patients, respectively. Arthralgia/arthritis occurred at a mean interval of 20 days (range 0-60 days). Knee was the most commonly involved joint (78.6%), followed by the wrist and metacarpophalangeal joints (each in 57.1%). Enthesitis was documented in 21.4% patients. The mean duration of COVID-19 associated arthralgia or arthritis was 53.9 days (range 7-210 days). In 85.7% patients, joint pains improved within 2 months;in only a small proportion of patients (14.3%), joint pains persisted after 6 months. Nonsteroidal anti-inflammatory drugs (NSAIDs) (given in 64.3% patients) and corticosteroids (in 50%) were the most commonly prescribed and effective treatment options.Conclusion:
COVID-19 infections mostly caused reactive arthritis, though acute and chronic arthritis is also seen. In the majority of cases, arthritis started about 3 weeks after COVID-19 infection and subsided within 2 months. NSAIDs and corticosteroids are the most effective treatment options.
adult; arthralgia; article; chronic arthritis; clinical article; clinical feature; controlled study; coronavirus disease 2019; drug therapy; enthesitis; female; fever; human; knee; male; metacarpophalangeal joint; myalgia; nasopharyngeal swab; observational study; reactive arthritis; reverse transcription polymerase chain reaction; wrist; corticosteroid; nonsteroid antiinflammatory agent
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Indian Journal of Rheumatology
Year:
2022
Document Type:
Article
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