Elevated risk of thrombotic manifestations of SARS-CoV-2 infection in cancer patients: A literature review.
EXCLI J
; 21: 906-920, 2022.
Article
in English
| MEDLINE | ID: covidwho-1928939
ABSTRACT
Coronavirus disease 2019 (COVID-19) results in higher risks of hospitalization or death in older patients and those with multiple comorbidities, including malignancies. Patients with cancer have greater risks of COVID-19 onset and worse prognosis. This excess is mainly explained by thrombotic complications. Indeed, an imbalance in the equilibrium between clot formation and bleeding, increased activation of coagulation, and endothelial dysfunction characterize both COVID-19 patients and those with cancer. With this review, we provide a summary of the pathological mechanisms of coagulation and thrombotic manifestations in these patients and discuss the possible therapeutic implications of these phenomena.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Prognostic study
/
Reviews
Language:
English
Journal:
EXCLI J
Year:
2022
Document Type:
Article
Affiliation country:
Excli2022-5073
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