Coronavirus Disease 2019 Vaccine Dosage in Children, Adolescents, and Young Adults: Is Less More?

Tobin, Nicole H; Yang, Otto O

Tobin, Nicole H; Yang, Otto O.

Tobin NH; Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Yang OO; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.

Open Forum Infect Dis ; 9(7): ofac222, 2022 Jul.

Article in English | MEDLINE | ID: covidwho-1931883

ABSTRACT

ABSTRACT

The lower efficacy of the COVID-19 mRNA vaccines in 5-11 year old children was unexpected. Neutralizing antibody titers elicited by the vaccines in children, adolescents, and young adults suggest that the lower efficacy is not due to the lower dosage. Confirming the efficacy of these vaccines in children, determining if mRNA vaccination strategies are less effective in younger children, as well as optimizing the dosage, dosing intervals, and number of doses needed in children, adolescents, and young adults are critical to improve vaccination strategies for these populations going forward.

Keywords

Boosters; COVID-19; COVID-19 vaccination; Covid-19 vaccination associated myocarditis; Dosage; Dosing intervals; Myocarditis; adolescents; children; young adults

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Topics: Vaccines Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google