Your browser doesn't support javascript.
Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization After Messenger RNA Vaccination and Variant Breakthrough Infection.
Gaebler, Christian; DaSilva, Justin; Bednarski, Eva; Muecksch, Frauke; Schmidt, Fabian; Weisblum, Yiska; Millard, Katrina G; Turroja, Martina; Cho, Alice; Wang, Zijun; Caskey, Marina; Nussenzweig, Michel C; Bieniasz, Paul D; Hatziioannou, Theodora.
  • Gaebler C; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • DaSilva J; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Bednarski E; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Muecksch F; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Schmidt F; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Weisblum Y; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Millard KG; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Turroja M; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Cho A; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Wang Z; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Caskey M; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Nussenzweig MC; Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, USA.
  • Bieniasz PD; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
  • Hatziioannou T; Laboratory of Retrovirology, The Rockefeller University, New York, New York, USA.
Open Forum Infect Dis ; 9(7): ofac227, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1931886
ABSTRACT
The emergence of severe acute respiratory syndrome coronavirus 2 variants that have greater transmissibility and resistance to neutralizing antibodies has increased the incidence of breakthrough infections. We show that breakthrough infection increases neutralizing antibody titers to varying degrees depending on the nature of the breakthrough variant and the number of vaccine doses previously administered. Omicron breakthrough infection resulted in neutralizing antibody titers that were the highest across all groups, particularly against Omicron.
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines / Variants Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Randomized controlled trials Topics: Vaccines / Variants Language: English Journal: Open Forum Infect Dis Year: 2022 Document Type: Article Affiliation country: Ofid