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Prognostic value of GRACE risk score in patients hospitalized for coronavirus disease 2019.
Dönmez, Esra; Özcan, Sevgi; Tugrul, Sevil; Ziyrek, Murat; Ince, Orhan; Nar Sagir, Gurur; Baran Yavuz, Mustafa; Gungor, Baris; Okuyan, Ertugrul; Sahin, Irfan.
  • Dönmez E; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Özcan S; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Tugrul S; Department of Cardiology, Basaksehir Çam and Sakura City Hospital.
  • Ziyrek M; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Ince O; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Nar Sagir G; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Baran Yavuz M; Department of Anesthesiology, Bagcilar Training and Research Hospital.
  • Gungor B; Department of Cardiology, University of Health Sciences Dr. Siyami Ersek Hospital, Istanbul, Turkey.
  • Okuyan E; Department of Cardiology, Bagcilar Training and Research Hospital.
  • Sahin I; Department of Cardiology, Bagcilar Training and Research Hospital.
Coron Artery Dis ; 33(6): 465-472, 2022 09 01.
Article in English | MEDLINE | ID: covidwho-1931944
ABSTRACT

OBJECTIVE:

COVID-19 pandemic continues to threaten human health as novel mutant variants emerge and disease severity ranges from asymptomatic to fatal. Thus, studies are needed to identify the patients with ICU need as well as those who have subsequent mortality. Global Registry of Acute Coronary Events (GRACE) risk score is a validated score in acute coronary syndrome. We aimed to evaluate if GRACE score can indicate adverse outcomes and major ischemic events in hospitalized COVID-19 patients.

METHODS:

All hospitalized patients due to COVID-19 at our institution between March 2020 and September 2020 were included in this retrospective study. Patients were grouped according to GRACE risk scores low risk 0-108 points, intermediate risk 109-140 and high risk ≥141.

RESULTS:

A total of 787 patients were enrolled; 434 patients formed group 1. One-hundred forty-one patients in group 2 and 212 patients formed group 3. We found that inhospital mortality, length of hospital stay, ICU and advanced ventilatory support need were associated with increasing GRACE risk score. In addition, major ischemic events were more frequently observed in higher risk groups and strong positive correlations between GRACE risk score and pro-BNP, procalcitonin and moderate positive correlation with D-dimer, CRP, NLR was found. Regression analysis showed that only GRACE risk score was an independent risk factor associated with inhospital mortality, major ischemic events, advanced ventilatory support and ICU need.

CONCLUSION:

The GRACE risk score is easy to apply on hospital admission and useful for classifying those in medium-high-intensity care units and to raise the assignments of sources.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Coronary Syndrome / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Variants Limits: Humans Language: English Journal: Coron Artery Dis Journal subject: Vascular Diseases / Cardiology Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Coronary Syndrome / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Variants Limits: Humans Language: English Journal: Coron Artery Dis Journal subject: Vascular Diseases / Cardiology Year: 2022 Document Type: Article