Bad news for Paxlovid? Resistance may be coming.

Service, Robert F

Service, Robert F.

Science ; 377(6602): 138-139, 2022 07 08.

Article in English | MEDLINE | ID: covidwho-1932606

ABSTRACT

ABSTRACT

In lab studies, SARS-CoV-2 finds ways to evade key drug. Some of the viral mutations are already found in people.

Subject(s)

COVID-19 Drug Treatment; Coronavirus 3C Proteases; Drug Resistance, Viral; Lactams; Leucine; Nitriles; Proline; Ritonavir; SARS-CoV-2; Viral Protease Inhibitors; Coronavirus 3C Proteases/antagonists & inhibitors; Coronavirus 3C Proteases/genetics; Drug Combinations; Drug Resistance, Viral/genetics; Humans; Lactams/pharmacology; Lactams/therapeutic use; Leucine/pharmacology; Leucine/therapeutic use; Mutation; Nitriles/pharmacology; Nitriles/therapeutic use; Proline/pharmacology; Proline/therapeutic use; Ritonavir/pharmacology; Ritonavir/therapeutic use; SARS-CoV-2/drug effects; SARS-CoV-2/genetics; Viral Protease Inhibitors/pharmacology; Viral Protease Inhibitors/therapeutic use

Fulltext

XML

PubMed Links

Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Proline / Ritonavir / Drug Resistance, Viral / Viral Protease Inhibitors / Coronavirus 3C Proteases / SARS-CoV-2 / COVID-19 Drug Treatment / Lactams / Leucine / Nitriles Limits: Humans Language: English Journal: Science Year: 2022 Document Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

PubMed Links

Search on Google