The First 110,593 COVID-19 Patients Hospitalised in Lombardy: A Regionwide Analysis of Case Characteristics, Risk Factors and Clinical Outcomes.
Int J Public Health
; 67: 1604427, 2022.
Article
in English
| MEDLINE | ID: covidwho-1933936
ABSTRACT
Objectives:
To describe the monthly distribution of COVID-19 hospitalisations, deaths and case-fatality rates (CFR) in Lombardy (Italy) throughout 2020.Methods:
We analysed de-identified hospitalisation data comprising all COVID-19-related admissions from 1 February 2020 to 31 December 2020. The overall survival (OS) from time of first hospitalisation was estimated using the Kaplan-Meier method. We estimated monthly CFRs and performed Cox regression models to measure the effects of potential predictors on OS.Results:
Hospitalisation and death peaks occurred in March and November 2020. Patients aged ≥70 years had an up to 180 times higher risk of dying compared to younger patients [70-80 HR 58.10 (39.14-86.22); 80-90 106.68 (71.01-160.27); ≥90 180.96 (118.80-275.64)]. Risk of death was higher in patients with one or more comorbidities [1 HR 1.27 (95% CI 1.20-1.35); 2 1.44 (1.33-1.55); ≥3 1.73 (1.58-1.90)] and in those with specific conditions (hypertension, diabetes).Conclusion:
Our data sheds light on the Italian pandemic scenario, uncovering mechanisms and gaps at regional health system level and, on a larger scale, adding to the body of knowledge needed to inform effective health service planning, delivery, and preparedness in times of crisis.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Int J Public Health
Journal subject:
Public Health
Year:
2022
Document Type:
Article
Affiliation country:
Ijph.2022.1604427
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