Serological prevalence of SARS-CoV-2 antibody among children and young age group (between 2 and 17 years) in India: An interim result from a large multicentric population-based seroepidemiological study.
J Family Med Prim Care
; 11(6): 2816-2823, 2022 Jun.
Article
in English
| MEDLINE | ID: covidwho-1934408
ABSTRACT
Background:
Estimating seroepidemiolgical prevalence of SARS-CoV-2 antibody is an essential public health strategy. There is insufficient evidence of prevalence among those belonging to young age population in India.Objective:
To compare the SARS-CoV-2 seropositivity rate between children and adults in selected sites from India. Materials andMethods:
This was a multicentric population-based seroepidemiological study conducted in selected urban and rural areas of five sites selected from four states (Delhi, Odisha, Uttar Pradesh, Tripura) of India. Participants aged ≥1 year were included from different clusters of each area. Total serum antibody against SARS-CoV-2 virus was assessed qualitatively by using a standard enzyme-linked immunosorbent assay (ELISA) kit.Results:
Data collection period was from 15 March 2021 to 10 June 2021. Total available data was of 4509 participants, of whom 700 were <18 years of age and 3809 were ≥18 years of age. The site-wise number of available data among those aged 2-17 years was 92, 189, 165, 146 and 108 for the sites of Delhi urban, Delhi rural, Bhubaneswar rural, Gorakhpur rural and Agartala rural area, respectively. The seroprevalence was 55.7% in the <18 years age group and 63.5% in the ≥18 years age group. The prevalence among female children was 58% and among male children was 53%.Conclusion:
SARS-CoV-2 seropositivity rate among children was high and comparable to that of the adult population. Hence, it is unlikely that any future third wave by prevailing SARS-CoV-2 variant would disproportionately infect children 2 years or older.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Observational study
/
Qualitative research
Topics:
Variants
Language:
English
Journal:
J Family Med Prim Care
Year:
2022
Document Type:
Article
Affiliation country:
Jfmpc.jfmpc_2274_21
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