New antivirals exploit viral feedback tricks for a cure without resistance.
Cell
; 185(13): 2210-2212, 2022 06 23.
Article
in English
| MEDLINE | ID: covidwho-1936136
ABSTRACT
Many approved drugs, including antivirals, are small-molecule inhibitors of disease-causing proteins. Such inhibitors often elicit resistance during treatment. Chaturvedi et al. propose new, feedback-disruptor (FD) antivirals that efficiently cure infected cells from viruses and minimize the chance of resistance, providing a new paradigm to treat viral infections and possibly other diseases.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Virus Diseases
Limits:
Humans
Language:
English
Journal:
Cell
Year:
2022
Document Type:
Article
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