RISK FACTORS FOR POST-COVID-19 SYNDROME DEVELOPMENT IN PATIENTS WITH ARTERIAL HYPERTENSION
Journal of Hypertension
; 40:e178, 2022.
Article
in English
| EMBASE | ID: covidwho-1937734
ABSTRACT
Objective:
To determine risk factors for post-COVID-19 syndrome development in patients with arterial hypertension (AH). Design andmethod:
A total of 81 patients with AH were examined 3-6 months after COVID-19. 48 people (group 1 27 women, 21 men) suffered from SARSCoV- 2 pneumonia with lungs lesion from 15% to 74%. The patients' age was 18-87 years old (65 years old on average). In 38 patients chronic ischemic heart disease (IHD) was diagnosed;in 18 - myocardial infarction (MI);in 10 - permanent atrial fibrillation (AF);in 12 - AF paroxysms. 33 people (group 2 18 women, 15 men) suffered from COVID-19 in the form of an acute respiratory illness without pneumonia. These patients were aged from 41 to 74 (56.9 years old on average). 25 patients had coronary artery disease;2 - MI;2 - permanent AF;4 - AF paroxysms.Results:
Comparing to group 2, in group 1 the patients had higher blood pressure;higher left atrial volume index (LAVI) (35.1 ± 3.3 ml/m2 vs. 29.6 ± 3.2 ml/m2;p < 0.05);higher left ventricular (LV) end-diastolic volume index (EDVI) (76.1 ± 8.8 ml/m2 vs. 62.6 ± 10.3 ml/m2;p < 0.05);lower LV ejection fraction (EF) (56.1 ± 8.1% vs. 63.2 ± 3.9%;p < 0.05). In 7 group 1 patients, an increase in the frequency of AF attacks was detected. In group 1 symptoms of inflammation persisted for a long time higher levels of C-reactive protein (15 ± 4.9 mg/l vs. 5.5 ± 3.8 mg/l), of blood ferritin (275 ± 106.3 mcg/l vs. 155.6 ± 85.8 mcg/l;p < 0.05), of D-dimer (919.3 ± 77.1 ng/ml vs. 609 ± 87.4 ng/ml;p < 0.05) as well as of total cholesterol (5.8 ± 1.2 mmol/l vs. 4.9 ± 1.1 mmol/l;p < 0.05) and of LDL (4.1 ± 1.1 mmol/l vs. 3.2 ± 1.3 mmol/l;p < 0.05).Conclusions:
The revealed risk factors were high blood pressure, an increase in LAVI and LV EDVI, a decrease in LVEF, an increase in LDL, previous MI, and an increase in the frequency of AF paroxysms.
C reactive protein; D dimer; endogenous compound; ferritin; low density lipoprotein; adult; aged; atrial fibrillation; blood pressure monitoring; cholesterol blood level; conference abstract; controlled study; coronary artery disease; coronavirus disease 2019; female; ferritin blood level; gene expression; heart infarction; heart left atrium; heart left ventricle ejection fraction; heart left ventricle enddiastolic volume; human; hypertension; inflammation; ischemic heart disease; long COVID; lung lesion; major clinical study; male; middle aged; permanent atrial fibrillation; pneumonia; protein expression; respiratory tract disease; risk factor; young adult
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Prognostic study
Topics:
Long Covid
Language:
English
Journal:
Journal of Hypertension
Year:
2022
Document Type:
Article
Similar
MEDLINE
...
LILACS
LIS