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Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Karki, Dipesh; Gurung, Roshani; Nepali, Prasanna; Kaphle, Hari Prasad; Subedi, Bhabuk; Adhikari, Sundar.
  • Karki D; Department of Medicine, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.
  • Gurung R; Pharmacy Programme, Gandaki University, Pokhara, Kaski, Nepal.
  • Nepali P; Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.
  • Kaphle HP; School of Health and Allied Sciences, Pokhara University, Pokhara, Kaski, Nepal.
  • Subedi B; Department of Intensive Care Unit, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.
  • Adhikari S; Department of Pharmacy, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal.
JNMA J Nepal Med Assoc ; 60(251): 596-599, 2022 Jul 01.
Article in English | MEDLINE | ID: covidwho-1939708
ABSTRACT

Introduction:

Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre.

Methods:

This descriptive cross-sectional study was conducted in COVID-19 unit of a tertiary care centre from 23 January 2021 to 19 June 2021. The ethical approval was taken from the Institutional Review Committee (Reference number 077/078/159). D-dimer values and demographic data of the hospital-admitted COVID-19 patients were recorded. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated.

Results:

Out of 180 patients with COVID-19 admitted in the hospital, the D-dimer levels were raised in 85 (47.22%) (39.93-54.51, 95% Confidence Interval) patients.

Conclusions:

The prevalence of raised D-dimer among admitted COVID-19 patients was found to be lower when compared to other studies conducted in similar settings. Keywords COVID-19; D-dimer; Nepal; prevalence.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Fibrin Fibrinogen Degradation Products / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: JNMA J Nepal Med Assoc Year: 2022 Document Type: Article Affiliation country: Jnma.7579

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Fibrin Fibrinogen Degradation Products / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: JNMA J Nepal Med Assoc Year: 2022 Document Type: Article Affiliation country: Jnma.7579