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Assessing the impact of novelty and conformity on hesitancy towards COVID-19 vaccines using mRNA technology.
Leong, Ching; Jin, Lawrence; Kim, Dayoung; Kim, Jeongbin; Teo, Yik Ying; Ho, Teck-Hua.
  • Leong C; Office of the Senior Deputy President and Provost, National University of Singapore, Singapore, Singapore.
  • Jin L; Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore, Singapore.
  • Kim D; Global Asia Institute, National University of Singapore, Singapore, Singapore.
  • Kim J; NUS Business School, National University of Singapore, Singapore, Singapore.
  • Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
  • Ho TH; Office of the Senior Deputy President and Provost, National University of Singapore, Singapore, Singapore.
Commun Med (Lond) ; 2: 61, 2022.
Article in English | MEDLINE | ID: covidwho-1947556
ABSTRACT

Background:

Public hesitancy towards Covid-19 vaccines remains a major hurdle for mass vaccination programs today. While mRNA vaccines are more efficacious than conventional vaccines, it is unknown how much the novelty of this technology increases hesitancy.

Methods:

We quantify this "novelty penalty" in a large online experiment with 35,173 adults in nine countries. Subjects were randomly selected and assigned to one of two vaccine groups (conventional or mRNA), and one of five hypothetical inoculation rate groups (0%, 20%, 40%, 60%, or 80%). Subjects reported their willingness to accept the Covid-19 vaccine on a five-point Likert scale.

Results:

The novelty of the mRNA vaccine technology reduces the odds of a higher level of vaccine acceptance by 14.2% (odds ratio 0.858; p < 0.001). On the other hand, we find that social conformity reduces vaccine hesitancy. At a 0% inoculation rate, 31.7% report that they are "very likely" to get a mRNA vaccine while at a 20% inoculation rate, willingness jumps to 49.6%.

Conclusions:

The novelty of the mRNA vaccine increases hesitancy, but social conformity reduces it. A small group of early adopters can provide momentum for vaccination.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: Commun Med (Lond) Year: 2022 Document Type: Article Affiliation country: S43856-022-00123-6

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials Topics: Vaccines Language: English Journal: Commun Med (Lond) Year: 2022 Document Type: Article Affiliation country: S43856-022-00123-6