SARS-CoV-2 variant strains and viral phylodynamics of ORF1a-1b genetic aspects in South America
2021 International Conference on Computational Science and Computational Intelligence, CSCI 2021
; : 330-336, 2021.
Article
in English
| Scopus | ID: covidwho-1948724
ABSTRACT
Bioinformatics tools for online sequence analysis of variants have been used worldwide for the phylogenetic approach of SARS-Cov-2 and their variants. The purpose of this work is to contribute to the settlement of the SARS-CoV-2 genetic of the South America pandemic, presenting the ORF1a-1b evaluation. We proposed and reviewed two online bioinformatics pipelines for viral phylodynamic and phylogeographic analysis with an interactive visualization platform. The phylodynamics evaluation of South America shows a strong viral capacity to evoke immunity and an impressive multiplicity of variants in rapid expansion with mutations of potential importance, including ORF 1a-1b. They showed stately vital for infection and lethality, spreading and raising your frequency in South America from 1% to 20-30% in one year of pandemic occurrence. © 2021 IEEE.
bioinformatics tools; in silico; phylogenetic tree; viral sequence depositories; Bioinformatics; Visualization; Bioinformatic tools; In-silico; Interactive visualizations; Phylogenetic approach; Phylogenetic trees; Rapid expansion; Sequence analysis; South America; Viral sequence depository; Visualization platforms; Coronavirus
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Topics:
Variants
Language:
English
Journal:
2021 International Conference on Computational Science and Computational Intelligence, CSCI 2021
Year:
2021
Document Type:
Article
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