Transient cryoglobulinaemic vasculitis following ChAdOx1 nCoV-19 vaccine.
BMJ Case Rep
; 15(7)2022 Jul 18.
Article
in English
| MEDLINE | ID: covidwho-1950070
ABSTRACT
Cryoglobulinaemic vasculitis is an immune-complex-mediated, systemic inflammatory syndrome usually involving small-to-medium vessels due to precipitation of cryoglobulins at <37°C. It can involve any organ but most commonly affects the skin. Associated conditions include infections (hepatitis C and HIV), haematological disorders (chronic lymphocytic lymphoma, monoclonal gammopathy of uncertain significance and multiple myeloma), autoimmune conditions (systemic lupus erythematosus and Sjogren syndrome) or as a complication following vaccination (influenza, pneumococcal and hepatitis B vaccines). Biochemical hallmarks include detection of serum cryoglobulin with low C4 levels. We describe a case of previous healthy patient with transient cryoglobulinaemic vasculitis after first dose of ChAdOx1 nCoV-19 vaccine (AstraZeneca/Oxford).
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Vasculitis
/
Sjogren's Syndrome
/
Cryoglobulinemia
Type of study:
Case report
/
Diagnostic study
Topics:
Long Covid
/
Vaccines
Limits:
Humans
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
Bcr-2022-250913
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