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Transient cryoglobulinaemic vasculitis following ChAdOx1 nCoV-19 vaccine.
Ahmer, Sadaf; Bourke, Jack; Ardakani, Nima Mesbah.
  • Ahmer S; Fiona Stanley Hospital, Murdoch, Western Australia, Australia sadaf.ahmer@health.wa.gov.au.
  • Bourke J; Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
  • Ardakani NM; Fiona Stanley Hospital, Murdoch, Western Australia, Australia.
BMJ Case Rep ; 15(7)2022 Jul 18.
Article in English | MEDLINE | ID: covidwho-1950070
ABSTRACT
Cryoglobulinaemic vasculitis is an immune-complex-mediated, systemic inflammatory syndrome usually involving small-to-medium vessels due to precipitation of cryoglobulins at <37°C. It can involve any organ but most commonly affects the skin. Associated conditions include infections (hepatitis C and HIV), haematological disorders (chronic lymphocytic lymphoma, monoclonal gammopathy of uncertain significance and multiple myeloma), autoimmune conditions (systemic lupus erythematosus and Sjogren syndrome) or as a complication following vaccination (influenza, pneumococcal and hepatitis B vaccines). Biochemical hallmarks include detection of serum cryoglobulin with low C4 levels. We describe a case of previous healthy patient with transient cryoglobulinaemic vasculitis after first dose of ChAdOx1 nCoV-19 vaccine (AstraZeneca/Oxford).
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vasculitis / Sjogren&apos;s Syndrome / Cryoglobulinemia Type of study: Case report / Diagnostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Bcr-2022-250913

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vasculitis / Sjogren&apos;s Syndrome / Cryoglobulinemia Type of study: Case report / Diagnostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Year: 2022 Document Type: Article Affiliation country: Bcr-2022-250913