Impact of SARS-CoV-2 infection on liver disease.
Adv Lab Med
; 3(2): 126-141, 2022 Jun.
Article
in English, Spanish
| MEDLINE | ID: covidwho-1951607
ABSTRACT
Introduction:
Abnormal liver biochemistry is not a rare finding in the context of SARS-CoV-2 infection, regardless of patients having pre-existing chronic disease or not. Content This review examines the current body of knowledge on the relationship between COVID-19 and liver injury, which is frequently found in this setting.Summary:
Although the pathogenesis of liver injury is not fully understood, it has been suggested to be the result of a combination of multiple factors. These include direct injury caused by the virus, immune system hyperactivation, ischemic and drug-induced injury. The prognostic valor of these alterations is also the subject of intense research. Due to their potential impact, these alterations require proper management and treatment, especially in patients with chronic liver disease or liver transplant recipients. Outlook Some aspects associated with liver injury during COVID-19, especially in severe presentations, are not well understood. Studies assessing the clinical impact of COVID-19 on the healthy or diseased liver may help adjust treatment and immunization guidelines to the profile of the patient.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Experimental Studies
Language:
English
/
Spanish
Journal:
Adv Lab Med
Year:
2022
Document Type:
Article
Affiliation country:
Almed-2022-0037
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