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Revealing the mystery of persistent smell loss in Long COVID patients.
Park, Jung Woo; Wang, Xiaoyan; Xu, Ren-He.
  • Park JW; Center of Reproduction, Development & Aging, and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.
  • Wang X; Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau, China.
  • Xu RH; Center of Reproduction, Development & Aging, and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.
Int J Biol Sci ; 18(12): 4795-4808, 2022.
Article in English | MEDLINE | ID: covidwho-1954695
ABSTRACT
COVID-19 is hopefully approaching its end in many countries as herd immunity develops and weaker strains of SARS-CoV-2 dominate. However, a new concern occurs over the long-term effects of COVID-19, collectively called "Long COVID", as some symptoms of the nervous system last even after patients recover from COVID-19. This review focuses on studies of anosmia, i.e., impairment of smell, which is the most common sensory defect during the disease course and is caused by olfactory dysfunctions. It remains mysterious how the olfactory functions are affected since the virus can't invade olfactory receptor neurons. We describe several leading hypotheses about the mystery in hope to provide insights into the pathophysiology and treatment strategies for anosmia.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Anosmia / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Int J Biol Sci Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Ijbs.73485

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Anosmia / COVID-19 Type of study: Diagnostic study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Int J Biol Sci Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Ijbs.73485