Updated progresses of acute hepatitis of unknown etiology in children and its management strategies

ABSTRACT

Acute hepatitis of unknown etiology in children has been reported in many countries all over the world since April 2022. As of May 27, there have been at least 650 cases of such patients reported by World Health Organization in 33 countries. The etiology of the hepatitis is still unknown. Adenovirus has been detected in samples of some cases, but it is also suspected that the immune response triggered by SARS-CoV-2 infection maybe contribute to the mechanism of the disease. In this paper, we overview the research and reports about the acute hepatitis of unknown etiology in children about its epidemiology, clinical features and possible etiology, then for the aim to make our country doing well in the monitoring and controlling of the acute hepatitis of unknown etiology in children. Here, we present some points of view from the perspective of infectious diseases and liver diseases in children.