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Factors affecting climacteric women with SARS-CoV-2 infection: A multinational Latin America study (REDLINC XI).
Vallejo, María S; Blümel, Juan E; Bencosme, Ascanio; Calle, Andrés; Dextre, Maribel; Díaz, Karen; López, Marcela; Miranda, Carlos; Ñañez, Mónica; Ojeda, Eliana; Rey, Claudia; Rodrigues, Marcio A; Salinas, Carlos; Tserotas, Konstantinos; Pérez-López, Faustino R.
  • Vallejo MS; Clínica Quilín, Facultad de Medicina, Universidad de Chile, Santiago de Chile, Chile.
  • Blümel JE; Departamento de Medicina Interna Sur, Facultad de Medicina, Universidad de Chile, Santiago de Chile, Chile. Electronic address: juan.blumel@redsalud.gov.cl.
  • Bencosme A; Ginecología Obstetricia, Hospital Metropolitano de Santiago, Santiago de los Caballeros, Dominican Republic.
  • Calle A; Centro Integral de Salud Obstétrica y Femenina-CISOF, Quito, Ecuador.
  • Dextre M; Ginecología Obstetricia, Clínica Internacional-Clínica Javier Prado, Lima, Peru.
  • Díaz K; Centro Ciudad Mujer, Ministerio de Salud, Asunción, Paraguay.
  • López M; Clínica Alemana y Hospital Militar, Santiago de Chile, Chile.
  • Miranda C; Hospital Central FAP-Instituto Médico Miraflores, Lima, Peru.
  • Ñañez M; II Cátedra de Ginecología, Universidad Nacional de Córdoba, Córdoba, Argentina.
  • Ojeda E; Departamento Académico de Medicina Humana, Universidad Andina del Cusco, Cusco, Peru.
  • Rey C; Medicina Ginecológica Consultorios Médicos, Buenos Aires, Argentina.
  • Rodrigues MA; Department Gynecology and Obstetrics, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Salinas C; Hospital Los Ángeles, Puebla, Mexico.
  • Tserotas K; Clínica Tserotas, Ciudad de Panamá, Panama.
  • Pérez-López FR; Instituto Aragonés de Ciencias de la Salud, Facultad de Medicina, Universidad de Zaragoza, Zaragoza, Spain.
Maturitas ; 165: 33-37, 2022 Nov.
Article in English | MEDLINE | ID: covidwho-1956262
ABSTRACT

OBJECTIVE:

To evaluate the association between factors, especially those linked to the climacteric, and a history of COVID-19 infection.

METHODS:

This was an observational, cross-sectional, and analytical study in which women from ten Latin American countries, aged 40-64, who attended a routine health check-up were invited to participate. A positive history for COVID-19 was based on reverse transcription-polymerase chain reaction reports. We evaluated sociodemographic, clinical, lifestyle, anthropometric variables, and menopausal symptoms using the Menopause Rating Scale (MRS).

RESULTS:

A total of 1238 women were included for analysis, of whom 304 (24.6 %) had a positive history for COVID-19. The median [interquartile range IQR] age of participants was 53 [IQR 12] years, duration of formal education was 16 [6] years, body mass index 25.6 [5.1] kg/m2, and total MRS score 10 [13]. In a logistic regression model, factors positively associated with COVID-19 included postmenopausal status and having a family history of dementia (OR 1.53; 95 % CI 1.13-2.07, and 2.40; 1.65-3.48, respectively), whereas negatively associated were use of menopausal hormone therapy (current or past), being a housewife, and being nulliparous (OR 0.47; 95 % CI 0.30-0.73; 0.72; 0.53-0.97 and 0.56; 0.34-0.92, respectively). Smoking, being sexually active, and use of hypnotics were also factors positively associated with COVID-19.

CONCLUSION:

Postmenopausal status and a family history of dementia were more frequent among women who had had COVID-19, and the infection was less frequent among current or past menopause hormone therapy users and in those with less physical contact.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Climacteric / Dementia / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans Language: English Journal: Maturitas Year: 2022 Document Type: Article Affiliation country: J.maturitas.2022.07.006

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Climacteric / Dementia / COVID-19 Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Female / Humans Language: English Journal: Maturitas Year: 2022 Document Type: Article Affiliation country: J.maturitas.2022.07.006