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Recent Advances in Chronotherapy Targeting Respiratory Diseases.
Paudel, Keshav Raj; Jha, Saurav Kumar; Allam, Venkata Sita Rama Raju; Prasher, Parteek; Gupta, Piyush Kumar; Bhattacharjee, Rahul; Jha, Niraj Kumar; Vishwas, Sukriti; Singh, Sachin K; Shrestha, Jesus; Imran, Mohammad; Panth, Nisha; Chellappan, Dinesh Kumar; Ebrahimi Warkiani, Majid; Hansbro, Philip M; Dua, Kamal.
  • Paudel KR; Centre for Inflammation, Centenary Institute, Sydney, NSW 2050, Australia.
  • Jha SK; School of Life Sciences, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • Allam VSRR; Department of Biomedicine, Health and Life Convergence Sciences, BK21 Four, Biomedical and Healthcare Research Institute, Mokpo National University, Muan 58554, Korea.
  • Prasher P; Department of Medical Biochemistry and Microbiology, Uppsala University, 75237 Uppsala, Sweden.
  • Gupta PK; Department of Chemistry, University of Petroleum & Energy Studies, Dehradun 248007, Uttarakhand, India.
  • Bhattacharjee R; Department of Life Sciences, School of Basic Sciences and Research, Sharda University, Greater Noida 201310, Uttar Pradesh, India.
  • Jha NK; Kalinga Institute of Industrial Technology (KIIT-DU), KIIT School of Biotechnology, Bhubaneswar 751024, Odisha, India.
  • Vishwas S; Department of Biotechnology, School of Engineering & Technology (SET), Sharda University, Plot No. 32-34, Knowledge Park III, Greater Noida 201310, Uttar Pradesh, India.
  • Singh SK; School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi Grand Trunk Road, Phagwara 144411, Punjab, India.
  • Shrestha J; School of Pharmaceutical Sciences, Lovely Professional University, Jalandhar-Delhi Grand Trunk Road, Phagwara 144411, Punjab, India.
  • Imran M; School of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • Panth N; Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, Delhi, India.
  • Chellappan DK; Centre for Inflammation, Centenary Institute, Sydney, NSW 2050, Australia.
  • Ebrahimi Warkiani M; School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia.
  • Hansbro PM; School of Biomedical Engineering, University of Technology Sydney, Sydney, NSW 2007, Australia.
  • Dua K; Institute for Biomedical Materials and Devices, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Pharmaceutics ; 13(12)2021 Nov 25.
Article in English | MEDLINE | ID: covidwho-1957413
ABSTRACT
Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep-wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual's circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Year: 2021 Document Type: Article Affiliation country: Pharmaceutics13122008

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Year: 2021 Document Type: Article Affiliation country: Pharmaceutics13122008