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Human coronavirus OC43 and its correlation with SARS-CoV-2
Chinese Journal of Microbiology and Immunology (China) ; 41(11):821-828, 2021.
Article in Chinese | EMBASE | ID: covidwho-1957485
ABSTRACT
Human coronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) belong to the β-coronavirus genus. Since the discovery in 1967, HCoV-OC43 has been continuously circulating in human population and has become one of the common seasonal respiratory viruses. SARS-CoV-2, which has a higher morbidity and fatality rate, appeared at the end of 2019, followed by the emergence of a variety of variants, and the transmission and infection capacity of SARS-CoV-2 has been enhanced. HCoV-OC43 may be similar to SARS-CoV-2 in terms of genomic structure and function, species evolution, epidemic characteristics and clinical manifestations. In this review, the epidemiology, genomics, phylogenetic evolution and other aspects of HCoV-OC43 and SARS-CoV-2 were analyzed. Such an analysis would be helpful to understand the association and differences between the two viruses, and provide reference for understanding the potential threats of HCoV-OC43.
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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: Chinese Journal: Chinese Journal of Microbiology and Immunology (China) Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: Chinese Journal: Chinese Journal of Microbiology and Immunology (China) Year: 2021 Document Type: Article