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Spotlight on therapeutic efficiency of mesenchymal stem cells in viral infections with a focus on COVID-19.
Yasamineh, Saman; Kalajahi, Hesam Ghafouri; Yasamineh, Pooneh; Gholizadeh, Omid; Youshanlouei, Hamed Rahmani; Matloub, Saeed Karimi; Mozafari, Masoud; Jokar, Elham; Yazdani, Yalda; Dadashpour, Mehdi.
  • Yasamineh S; Department of Medical Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Kalajahi HG; Young Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
  • Yasamineh P; Department of Biotechnology, Institute of Science, Uskudar University, Istanbul, Turkey.
  • Gholizadeh O; Young Researchers and Elite Club, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
  • Youshanlouei HR; Department of Bacteriology and Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Matloub SK; Department of Internal Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Mozafari M; Students Research Committee, Qom University of Medical Sciences, Qom, Iran.
  • Jokar E; Cardiovascular Pharmacology Research Lab, Department of Pharmacology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Yazdani Y; Department of Medical Chemistry, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
  • Dadashpour M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. yaldayznn@gmail.com.
Stem Cell Res Ther ; 13(1): 257, 2022 06 17.
Article in English | MEDLINE | ID: covidwho-1962893
ABSTRACT
The SARS-COV-2 virus has infected the world at a very high rate by causing COVID-19 disease. Nearly 507 million individuals have been infected with this virus, with approximately 1.2% of these patients being dead, indicating that this virus has been out of control in many countries. While researchers are investigating how to develop efficient drugs and vaccines versus the COVID-19 pandemic, new superseded treatments have the potential to reduce mortality. The recent application of mesenchymal stem cells (MSCs) in a subgroup of COVID-19 patients with acute respiratory distress has created potential benefits as supportive therapy for this viral contagion in patients with acute conditions and aged patients with severe pneumonia. Consequently, within this overview, we discuss the role and therapeutic potential of MSCs and the challenges ahead in using them to treat viral infections, with highlighting on COVID-19 infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells / COVID-19 Topics: Vaccines Limits: Aged / Humans Language: English Journal: Stem Cell Res Ther Year: 2022 Document Type: Article Affiliation country: S13287-022-02944-7

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Mesenchymal Stem Cell Transplantation / Mesenchymal Stem Cells / COVID-19 Topics: Vaccines Limits: Aged / Humans Language: English Journal: Stem Cell Res Ther Year: 2022 Document Type: Article Affiliation country: S13287-022-02944-7