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Treating patients infected with the SARS-CoV-2 Omicron variant with a traditional Chinese medicine, Shufeng Jiedu capsule.
Zhang, Jing; Liu, Lili; Zhang, Guoliang; Li, Mingqiang; Ma, Bitao; Yang, Wenming.
  • Zhang J; Department of Internal Medicine, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
  • Liu L; Department of Infection, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
  • Zhang G; Department of Infection, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
  • Li M; Department of Traditional Chinese Medicine, the First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, China.
  • Ma B; Department of Traditional Chinese Medicine, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Yang W; Department of Internal Medicine, the First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.
Biosci Trends ; 16(3): 238-241, 2022 Jul 20.
Article in English | MEDLINE | ID: covidwho-1964370
ABSTRACT
Patients infected with the Omicron variant of SARS-CoV-2 mainly develop mild COVID-19, manifesting as upper respiratory symptoms, fatigue, and fever. Shufeng Jiedu capsule (SFJDC), a traditional Chinese medicine indicated for treatment of upper respiratory infections in China, was tested for its efficacy and safety in treatment of an Omicron infection at a mobile cabin hospital in response to an outbreak of COVID-19 in Shanghai, China in April 2022. In this open-label, randomized controlled trial, patients in the control group received best supportive care, while those in the test group received additional SFJDC therapy for 7 days. SFJDC markedly alleviated patients' symptoms including a sore throat, coughing, fatigue, and a fever after 7 days of treatment. The virus negative time was significantly shorter in the SFJDC treatment group, but there were no obvious differences in the virus negative rate between the two groups at the end of the 7-day follow-up. These results suggest that patients with the Omicron infection may benefit from SFJDC treatment. Double-blind, randomized controlled trials are warranted to comprehensively evaluate the efficacy and safety of SFJDC in a large cohort study in the future.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Traditional medicine / Variants Limits: Humans Country/Region as subject: Asia Language: English Journal: Biosci Trends Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Bst.2022.01220

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Topics: Traditional medicine / Variants Limits: Humans Country/Region as subject: Asia Language: English Journal: Biosci Trends Journal subject: Biology Year: 2022 Document Type: Article Affiliation country: Bst.2022.01220