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Suicide numbers during the first 9-15 months of the COVID-19 pandemic compared with pre-existing trends: An interrupted time series analysis in 33 countries.
Pirkis, Jane; Gunnell, David; Shin, Sangsoo; Del Pozo-Banos, Marcos; Arya, Vikas; Aguilar, Pablo Analuisa; Appleby, Louis; Arafat, S M Yasir; Arensman, Ella; Ayuso-Mateos, Jose Luis; Balhara, Yatan Pal Singh; Bantjes, Jason; Baran, Anna; Behera, Chittaranjan; Bertolote, Jose; Borges, Guilherme; Bray, Michael; Brecic, Petrana; Caine, Eric; Calati, Raffaella; Carli, Vladimir; Castelpietra, Giulio; Chan, Lai Fong; Chang, Shu-Sen; Colchester, David; Coss-Guzmán, Maria; Crompton, David; Curkovic, Marko; Dandona, Rakhi; De Jaegere, Eva; De Leo, Diego; Deisenhammer, Eberhard A; Dwyer, Jeremy; Erlangsen, Annette; Faust, Jeremy S; Fornaro, Michele; Fortune, Sarah; Garrett, Andrew; Gentile, Guendalina; Gerstner, Rebekka; Gilissen, Renske; Gould, Madelyn; Gupta, Sudhir Kumar; Hawton, Keith; Holz, Franziska; Kamenshchikov, Iurii; Kapur, Navneet; Kasal, Alexandr; Khan, Murad; Kirtley, Olivia J.
  • Pirkis J; Centre for Mental Health, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
  • Gunnell D; National Institute of Health and care Research Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, United Kingdom.
  • Shin S; Centre for Mental Health, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
  • Del Pozo-Banos M; Swansea University Medical School, Swansea, United Kingdom.
  • Arya V; Centre for Mental Health, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
  • Aguilar PA; Ministry of Public Health, Department of Health Promotion, Quito, Ecuador.
  • Appleby L; National Confidential Inquiry into Suicide and Safety in Mental Health, University of Manchester, Manchester, United Kingdom.
  • Arafat SMY; Department of Psychiatry, Enam Medical College and Hospital, Dhaka, Bangladesh.
  • Arensman E; School of Public Health, National Suicide Research Foundation, University College Cork, Cork, Ireland.
  • Ayuso-Mateos JL; Australian Institute for Suicide Research and Prevention, School of Applied Psychology, Griffith University, Brisbane, Australia.
  • Balhara YPS; Department of Psychiatry, Universidad Autonoma de Madrid, Centre for Biomedical Research in Mental Health (CIBERSAM), Madrid, Spain.
  • Bantjes J; National Drug Dependence Treatment Center and Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
  • Baran A; Alcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council, Cape Town, South Africa.
  • Behera C; Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Stellenbosch, South Africa.
  • Bertolote J; Working Group on Prevention of Suicide and Depression at Public Health Council, Ministry of Health, Warsaw, Poland.
  • Borges G; Department of Medicine and Optometry, Linnaeus University, Kalmar, Sweden.
  • Bray M; Department of Psychiatry, Blekinge Hospital, Karlshamn, Sweden.
  • Brecic P; Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, India.
  • Caine E; Department of Neurology, Psychology and Psychiatry, Botucatu Medical School, Universidade Estadual Paulista (UNESP), Botucatu, Brazil.
  • Calati R; Department of Global Mental Health, Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz, Mexico City, Mexico.
  • Carli V; Department of Psychiatry and Behavioural Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
  • Castelpietra G; Department for Psychiatry, University Psychiatric Hospital Vrapce; School of Medicine University of Zagreb, Zagreb, Croatia.
  • Chan LF; University of Rochester Medical Center, Rochester, NY, United States.
  • Chang SS; Department of Psychology, University of Milan-Bicocca, Milan, Italy.
  • Colchester D; Department of Psychiatry, Nimes University Hospital, Nimes, France.
  • Coss-Guzmán M; National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institutet, Stockholm, Sweden.
  • Crompton D; Region Friuli Venezia Giulia, Central Health Directorate, Outpatient and Inpatient Care Service, Trieste, Italy.
  • Curkovic M; Department of Psychiatry, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia.
  • Dandona R; Institute of Health Behaviors and Community Sciences, College of Public Health, National Taiwan University, Taipei, Taiwan.
  • De Jaegere E; Thames Valley Police, Bicester, United Kingdom.
  • De Leo D; Puerto Rico Department of Health's Commission on Suicide Prevention, San Juan, Puerto Rico.
  • Deisenhammer EA; School of Applied Psychology, Griffith University, Brisbane, Australia.
  • Dwyer J; Department for Medical Ethics, University Psychiatric Hospital Vrapce; School of Medicine University of Zagreb, Zagreb, Croatia.
  • Erlangsen A; Public Health Foundation of India, Gurugram, India.
  • Faust JS; Institute for Health Metrics and Evaluation, University of Washington, Seattle, United States.
  • Fornaro M; Flemish Centre of Expertise in Suicide Prevention, Department of Head and Skin, Ghent University, Ghent, Belgium.
  • Fortune S; Griffith University, Brisbane, Australia.
  • Garrett A; Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology; University Hospital for Psychiatry 2, Medical University of Innsbruck, Innsbruck, Austria.
  • Gentile G; Coroners Court of Victoria, Melbourne, Australia.
  • Gerstner R; Danish Research Institute for Suicide Prevention, Mental Health Centre Copenhagen, Copenhagen, Denmark.
  • Gilissen R; Copenhagen Research Centre for Mental Health, Copenhagen, Denmark.
  • Gould M; Centre for Mental Health Research, Australian National University, Canberra, Australia.
  • Gupta SK; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
  • Hawton K; Brigham and Women's Hospital Department of Emergency Medicine, Harvard Medical School, Boston, United States.
  • Holz F; Department of Psychiatry, Neuroscience Institute, Federico II University of Naples, Naples, Italy.
  • Kamenshchikov I; School of Population Health, The University of Auckland, Auckland, New Zealand.
  • Kapur N; Coronial Division, Tasmanian Magistrates Court, Hobart, Australia.
  • Kasal A; Institute of Forensic Medicine, Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
  • Khan M; Undersecretary of Health Services, Ministry of Public Health, Quito, Ecuador.
  • Kirtley OJ; Monitoring and Evaluation, German Institute for Medical Mission, Tübingen, Germany.
EClinicalMedicine ; 51: 101573, 2022 Sep.
Article in English | MEDLINE | ID: covidwho-1966513
ABSTRACT

Background:

Predicted increases in suicide were not generally observed in the early months of the COVID-19 pandemic. However, the picture may be changing and patterns might vary across demographic groups. We aimed to provide a timely, granular picture of the pandemic's impact on suicides globally.

Methods:

We identified suicide data from official public-sector sources for countries/areas-within-countries, searching websites and academic literature and contacting data custodians and authors as necessary. We sent our first data request on 22nd June 2021 and stopped collecting data on 31st October 2021. We used interrupted time series (ITS) analyses to model the association between the pandemic's emergence and total suicides and suicides by sex-, age- and sex-by-age in each country/area-within-country. We compared the observed and expected numbers of suicides in the pandemic's first nine and first 10-15 months and used meta-regression to explore sources of variation.

Findings:

We sourced data from 33 countries (24 high-income, six upper-middle-income, three lower-middle-income; 25 with whole-country data, 12 with data for area(s)-within-the-country, four with both). There was no evidence of greater-than-expected numbers of suicides in the majority of countries/areas-within-countries in any analysis; more commonly, there was evidence of lower-than-expected numbers. Certain sex, age and sex-by-age groups stood out as potentially concerning, but these were not consistent across countries/areas-within-countries. In the meta-regression, different patterns were not explained by countries' COVID-19 mortality rate, stringency of public health response, economic support level, or presence of a national suicide prevention strategy. Nor were they explained by countries' income level, although the meta-regression only included data from high-income and upper-middle-income countries, and there were suggestions from the ITS analyses that lower-middle-income countries fared less well.

Interpretation:

Although there are some countries/areas-within-countries where overall suicide numbers and numbers for certain sex- and age-based groups are greater-than-expected, these countries/areas-within-countries are in the minority. Any upward movement in suicide numbers in any place or group is concerning, and we need to remain alert to and respond to changes as the pandemic and its mental health and economic consequences continue.

Funding:

None.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials / Reviews Language: English Journal: EClinicalMedicine Year: 2022 Document Type: Article Affiliation country: J.eclinm.2022.101573

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Prognostic study / Randomized controlled trials / Reviews Language: English Journal: EClinicalMedicine Year: 2022 Document Type: Article Affiliation country: J.eclinm.2022.101573