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Immediate reinfection with Omicron variant after clearance of a previous SARS-CoV-2 infection.
Mencacci, Antonella; Gili, Alessio; Camilloni, Barbara; Bicchieraro, Giulia; Spaccapelo, Roberta; Bietta, Carla; Stracci, Fabrizio.
  • Mencacci A; Microbiology and Clinical Microbiology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy. Electronic address: antonella.mencacci@unipg.it.
  • Gili A; Public Health Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Camilloni B; Microbiology and Clinical Microbiology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Bicchieraro G; Microbiology and Clinical Microbiology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Spaccapelo R; Microbiology and Clinical Microbiology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.
  • Bietta C; Epidemiology Unit, Department of Preventive Medicine, Local Health Unit 1, Umbria region, Italy.
  • Stracci F; Public Health Section, Department of Medicine and Surgery, University of Perugia, Perugia, Italy. Electronic address: fabrizio.stracci@unipg.it.
J Infect Public Health ; 15(9): 983-985, 2022 Sep.
Article in English | MEDLINE | ID: covidwho-1966859
ABSTRACT
SARS-CoV-2 Omicron variant is spreading worldwide, causing unprecedented epidemic peaks due to its transmissibility and immune evasion. We searched in the archive of the Regional Microbiology Laboratory (Umbria, Italy) for immediate reinfection (i.e. infection occurring 25-60 days from primary infection) among 454,764 RT-PCR tests from 261,217 individuals. Lineage heterogeneity was assessed by S gene target failure phenomenon or whole genome sequencing. We found that BA.1 Omicron variant may cause immediate reinfection of patients just recovered from Delta infection. Immediate reinfection was not observed for any other combination of variants, including Delta over Alpha variant and BA.2 over BA.1 Omicron lineage.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study Topics: Variants Limits: Humans Country/Region as subject: Europa Language: English Journal: J Infect Public Health Journal subject: Communicable Diseases / Public Health Year: 2022 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study Topics: Variants Limits: Humans Country/Region as subject: Europa Language: English Journal: J Infect Public Health Journal subject: Communicable Diseases / Public Health Year: 2022 Document Type: Article