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Impact and Value of Hospital Antibiotic Stewardship: Retrospective Pre-COVID-19-Pandemic Analysis.
Costantino, Maria; Conti, Valeria; Corbi, Graziamaria; Iannelli, Alessandra Anna; Marongiu, Francesco; Torsiello, Martina; Della Vecchia, Antonio; Sellitto, Carmine; Genovese, Armando; Moccia, Giuseppina; Filippelli, Amelia; De Caro, Francesco.
  • Costantino M; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.
  • Conti V; University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84121 Salerno, Italy.
  • Corbi G; Association Non-Profit F.I.R.S.Thermae (Interdisciplinary Training, Researches and Spa Sciences), 80078 Naples, Italy.
  • Iannelli AA; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.
  • Marongiu F; University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84121 Salerno, Italy.
  • Torsiello M; Department of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
  • Della Vecchia A; Italian Society of Gerontology and Geriatrics (SIGG), 50129 Florence, Italy.
  • Sellitto C; University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84121 Salerno, Italy.
  • Genovese A; Association Non-Profit F.I.R.S.Thermae (Interdisciplinary Training, Researches and Spa Sciences), 80078 Naples, Italy.
  • Moccia G; Department of Industrial Engineering, University of Salerno, 84084 Fisciano, Italy.
  • Filippelli A; Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", 84081 Baronissi, Italy.
  • De Caro F; General Directorate of Health Planning, Office 3-Italian Ministry of Health, 00144 Roma, Italy.
J Clin Med ; 11(15)2022 Jul 29.
Article in English | MEDLINE | ID: covidwho-1969315
ABSTRACT

AIM:

"Antimicrobial stewardship" (AMS) is defined as a healthcare-system-wide approach to promoting and monitoring the judicious use of antimicrobials to preserve their future effectiveness. Therefore, we structured an observational study to monitor the hospital trend of antibiotic consumption and related expenditure before the COVID-19 pandemic and to evaluate how much AMS could affect this trend.

METHODS:

The research covered the antibiotic prescriptions at the University Hospital (U.H.) "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy, comparing data on the therapies prescribed from 1 January to 31 December 2017 (27,384 patients) with those collected during the same period in 2019 (27,047 patients).

RESULTS:

Unlike national data, our results highlighted a decreasing trend in the consumption of antibiotics that did not concern only carbapenems and fluoroquinolones, but also the third-generation cephalosporins. Noteworthily, there was also a reduction in 2019 compared with 2017 in the consumption of colistin, an antibiotic towards which an increase in bacterial resistance in animals has been found nationally. In agreement with the national data, our research confirms a trend of an increase (+3.7%) in the total antibiotic consumption corresponding to more than 26% and 29% reductions in the total and therapy per-day costs, respectively.

CONCLUSIONS:

The results show a positive impact of the AMS at the University Hospital "San Giovanni di Dio e Ruggi d'Aragona".
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Jcm11154412

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Year: 2022 Document Type: Article Affiliation country: Jcm11154412