Dipeptidyl peptidase 4 and its function against COVID-19
Revista Cubana de Medicina
; 61(1), 2022.
Article
in Spanish
| CAB Abstracts | ID: covidwho-1970791
ABSTRACT
Given the appearance of a "new virus" in the of Wuhan city, China, called SARSCoV- 2, which causes the well-known severe acute respiratory syndrome (COVID- 19), many scientists are trying to find a solution against the virus that has caused a pandemic. In this search, a transmembrane glycoprotein called dipeptidyl peptidase 4 or DPP-4 was found present on the surface of different types of cells and a target in MERS-Co-V infection, which opens hope by suspecting that DPP- 4 can be a target in different coronaviruses by serving as a therapeutic strategy. Added to this, there are results that find elevated DPP-4 in patients with severe complications from COVID-19, which may be a possible marker of severity. However, there is still little emphasis on the identification and association of this glycoprotein with COVID-19. To this effect, a bibliographic review was carried out on the most significant aspects of Dipeptidyl Peptidase 4 and its function against COVID-19.
Prion, Viral, Bacterial and Fungal Pathogens of Humans [VV210]; Pesticides and Drugs; Control [HH405]; dipeptidyl peptidase IV inhibitors; coronavirus disease 2019; viral diseases; human diseases; therapy; severe course; disease markers; acute course; Severe acute respiratory syndrome coronavirus 2; man; Hubei; China; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; Central Southern China; APEC countries; East Asia; Asia; high Human Development Index countries; upper-middle income countries; SARS-CoV-2; viral infections; Hopei; Hupei; therapeutics; People's Republic of China
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
Spanish
Journal:
Revista Cubana de Medicina
Year:
2022
Document Type:
Article
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