EmBmem: will the real memory B cell please stand up?

Dhenni, Rama; Phan, Tri Giang

Dhenni, Rama; Phan, Tri Giang.

Dhenni R; Precision Immunology Program, Garvan Institute of Medical Research, Sydney, NSW, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia.
Phan TG; Precision Immunology Program, Garvan Institute of Medical Research, Sydney, NSW, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia; ACRF INCITe Centre, Garvan Institute of Medical Research, Sydney, NSW, Australia. Electronic address: t.phan@garvan.org.au.

Trends Immunol ; 43(8): 595-597, 2022 08.

Article in English | MEDLINE | ID: covidwho-1972142

ABSTRACT

ABSTRACT

Lung-resident memory B cells (Bmems) rapidly differentiate into localized effectors to generate neutralizing antibodies and protect against reinfection of the tissue. Using lineage tracing, Gregoire et al. now show that lung-resident Bmems may also include bystanders generated by an alternative permissive differentiation pathway.

Subject(s)

Immunologic Memory; Memory B Cells; Antibodies, Neutralizing; Humans; Lung

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Memory B Cells / Immunologic Memory Limits: Humans Language: English Journal: Trends Immunol Journal subject: Allergy and Immunology Year: 2022 Document Type: Article Affiliation country: J.it.2022.05.001

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