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COVID-19-associated fungal infections.
Hoenigl, Martin; Seidel, Danila; Sprute, Rosanne; Cunha, Cristina; Oliverio, Matteo; Goldman, Gustavo H; Ibrahim, Ashraf S; Carvalho, Agostinho.
  • Hoenigl M; Division of Infectious Diseases, Department of Internal Medicine, Medical University of Graz, Graz, Austria. hoeniglmartin@gmail.com.
  • Seidel D; Division of Infectious Diseases and Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA, USA. hoeniglmartin@gmail.com.
  • Sprute R; Clinical and Translational Fungal Working Group, University of California San Diego, La Jolla, CA, USA. hoeniglmartin@gmail.com.
  • Cunha C; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Chair Translational Research, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Oliverio M; Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Goldman GH; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Chair Translational Research, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Ibrahim AS; Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Carvalho A; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal.
Nat Microbiol ; 7(8): 1127-1140, 2022 08.
Article in English | MEDLINE | ID: covidwho-1972610
ABSTRACT
Coronavirus disease 2019 (COVID-19)-associated invasive fungal infections are an important complication in a substantial number of critically ill, hospitalized patients with COVID-19. Three groups of fungal pathogens cause co-infections in COVID-19 Aspergillus, Mucorales and Candida species, including Candida auris. Here we review the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries. By evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, we set the scene for future research and development of clinical guidance.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coinfection / Invasive Fungal Infections / COVID-19 / Mycoses Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Nat Microbiol Year: 2022 Document Type: Article Affiliation country: S41564-022-01172-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coinfection / Invasive Fungal Infections / COVID-19 / Mycoses Type of study: Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Humans Language: English Journal: Nat Microbiol Year: 2022 Document Type: Article Affiliation country: S41564-022-01172-2