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Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation.
Phan, Phuc H; Nguyen, Dung T; Dao, Nam H; Nguyen, Ha T T; Vu, An V; Hoang, Son T; Nguyen, Lam V; Cao, Tung V; Tran, Dien M.
  • Phan PH; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Nguyen DT; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Dao NH; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Nguyen HTT; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Vu AV; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Hoang ST; Cardiovascular Center, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Nguyen LV; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Cao TV; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
  • Tran DM; Pediatric COVID-19 Intensive Care Unit, Vietnam National Children's Hospital, Hanoi, Vietnam.
Front Pediatr ; 10: 946547, 2022.
Article in English | MEDLINE | ID: covidwho-1974671
ABSTRACT

Background:

Indirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of instituting veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support for cardiac compromise has been reported. However, current literature enunciates a paucity of available data on the effectiveness of these novel modalities. Case Presentation We reported a 9-year-old boy with recurrent COVID-19 infection-causing fulminant myocarditis, who was treated successfully by using novel modalities of oXiris ® hemofilter continuous venovenous hemofiltration (CVVH) and VA-ECMO. The patient made a full recovery without any sequelae.

Conclusion:

We conclude that the novel highly-absorptive hemofilter CVVH and VA-ECMO may be effective treatment modalities in managing SARS-CoV-2-induced fulminant myocarditis. Our report highlights the need for further well-designed investigations to confirm this extrapolation.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Topics: Long Covid Language: English Journal: Front Pediatr Year: 2022 Document Type: Article Affiliation country: Fped.2022.946547

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Topics: Long Covid Language: English Journal: Front Pediatr Year: 2022 Document Type: Article Affiliation country: Fped.2022.946547