Research progress in novel coronavirus (2019-nCoV)-related drugs in vitro and in vivo

ABSTRACT

In December 2019 in Wuhan City (Hubei Province, China), multiple cases of patients with pneumonia infected by a new type of coronavirus were noted. With the spread of the epidemic, other cases in China and overseas have also been found. On 12 January 2020, the World Health Organization tentatively named it "2019 Novel Coronavirus" (2019-nCoV). This is a new type of virus, which is highly infectious and can cause severe respiratory diseases. A clinically efficacious treatment is lacking. We reviewed the guidelines for recommended therapeutic drugs and drug-development advances with the aim of providing a reference for clinical treatment of 2019-nCoV infection.