Factors related to longterm anticoagulation in cvt patients from a tertiary hospital
European Journal of Neurology
; 29:703, 2022.
Article
in English
| EMBASE | ID: covidwho-1978466
ABSTRACT
Background and aims:
Anticoagulation on CVT is followed until 6 to 12 months according to guidelines. Longer periods of treatment are used in patients with high thrombotic risk. We describe the duration of treatment with OAC and what risk factors are related to longer treatment.Methods:
We conducted a retrospective single centre study in a tertiary hospital in México City. Electronic medical files of consecutive patients with CVT were reviewed from January 2018 to June 2020. Clinical, radiological and laboratory variables were obtained. Patients were allocated according to the time of use of OAC (less or more than a year).Results:
We collected data from 20 patients. 14 (70%) were female, with a mean age of 33.5 (26-50). 40% (n=8) were smokers, 20% (n=4) used hormonal contraceptives, 15% (n=3) were pregnant or in puerperium and 10% (n=2) referred vaccination for SARS-CoV-2. superior sagittal sinus was the most frequently affected (65%). The median time of AOC treatment was 13 months (6.7-16.7). In the bivariate analysis, the existence of a chronic cause (OR 14;IC95%, 1.25-156;p= 0.028), and prolonged hospitalization (OR 15.7;IC95% 1.7-141.4 p= 0.22) were associated with AOC treatment over a year. Initial NIHSS, mRS at discharge, D-dimer values or seizures al presentation showed no correlation.Conclusion:
Use of OAC in a tertiary centre is related to chronic conditions with high thrombotic risk and with long hospital stay, according to the guideline's recommendations.
D dimer; hormonal contraceptive agent; adult; anticoagulation; bivariate analysis; chronic disease; clinical article; conference abstract; controlled study; drug therapy; female; hospitalization; human; IC95; male; National Institutes of Health Stroke Scale; nonhuman; practice guideline; pregnancy; puerperium; Rankin scale; retrospective study; risk factor; seizure; Severe acute respiratory syndrome coronavirus 2; smoking; superior sagittal sinus; tertiary care center; thrombosis; treatment duration; vaccination
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Language:
English
Journal:
European Journal of Neurology
Year:
2022
Document Type:
Article
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