Prognostic Value of Chest-Computed Tomography in Patients with COVID-19.
Adv Respir Med
; 90(4): 312-322, 2022 Aug 09.
Article
in English
| MEDLINE | ID: covidwho-1979104
ABSTRACT
BACKGROUND:
The diagnostic value for chest CT has been widely established in patients with COVID-19. However, there is a lack of satisfactory data about the prognostic value of chest CTs. This study investigated the prognostic value of chest CTs in COVID-19 patients. MATERIALS ANDMETHODS:
A total of 521 symptomatic patients hospitalized with COVID-19 were included retrospectively. Clinical, laboratory, and chest CT characteristics were compared between survivors and non-survivors. Concerning chest CT, for each subject, a semi-quantitative CT severity scoring system was applied.RESULTS:
Most patients showed typical CT features based on the likelihood of COVID-19. The global CT score was significantly higher in non-survivors (median (IQR), 1 (0-6) vs. 10 (5-13), p < 0.001). A cut-off value of 5.5 for the global CT score predicted in-hospital mortality with 74% sensitivity and 73% specificity. Global CT score, age, C-reactive protein, and diabetes were independent predictors of in-hospital mortality. The global CT score was significantly correlated with the C-reactive protein, D-dimer, pro-brain natriuretic peptide, and procalcitonin levels.CONCLUSION:
The global CT score could provide valuable prognostic data in symptomatic patients with COVID-19.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Adv Respir Med
Year:
2022
Document Type:
Article
Affiliation country:
Arm90040041
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