PEDV: Insights and Advances into Types, Function, Structure, and Receptor Recognition.
Viruses
; 14(8)2022 08 09.
Article
in English
| MEDLINE | ID: covidwho-1979415
ABSTRACT
Porcine epidemic diarrhea virus (PEDV) has been endemic in most parts of the world since its emergence in the 1970s. It infects the small intestine and intestinal villous cells, spreads rapidly, and causes infectious intestinal disease characterized by vomiting, diarrhea, and dehydration, leading to high mortality in newborn piglets and causing massive economic losses to the pig industry. The entry of PEDV into cells is mediated by the binding of its spike protein (S protein) to a host cell receptor. Here, we review the structure of PEDV, its strains, and the structure and function of the S protein shared by coronaviruses, and summarize the progress of research on possible host cell receptors since the discovery of PEDV.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Swine Diseases
/
Coronavirus Infections
/
Coronavirus
/
Porcine epidemic diarrhea virus
Limits:
Animals
Language:
English
Year:
2022
Document Type:
Article
Affiliation country:
V14081744
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