Clinical profile and outcomes of COVID 19 patients having acute kidney injury: an experience from a tertiary care centre Eastern India

ABSTRACT

Introduction: SARS COVID 19 is the third corona virus affecting all over the world in last 20 years following SARS COV and MERS COV. Multiple complications and death usually occurs in 6.4 % cases. In the beginning reports, incidence of AKI was negligible. Various data shows AKI occurs is >20% hospitalized patients and >50% of ICU patients. Methods: The study was a cross sectional study, carried out in the department of nephrology, of IMS and SUM Hospital, Bhubaneswar for a period of 1.2 years (April 2020-June 2021). The patients data was obtained from the hospital information system (HIS). It included the individuals of at least 18 years old, with a laboratory confirmed SARS-COV2 infection, and were hospitalised for the same. It excluded the known ESKD prior to admission and patients who were hospitalised for less than 48 hours. Results: It was observed that most patients were in their 6th decade, 40 % were Female. Patients with AKI, have low Hb%,high TLC count, low platelet count, high potassium level and low albumin, bicarbonate level,lymphocyte count, and higher creatinine values. Out of 3993 patients, 46% 1 developed AKI. In ICU 76% developed AKI. Peak Serum Creatinine was 2.2(IQR 1.5-3.6) in non dialysis patients and 8.2 in dialysis requiring patients (IQR 6.1-11). Conclusion: It is not uncommon to come across AKI patients in patients suffering from COVID-19 also associated with high death rate. Meticulous clinical observation and instillation of therapy helps to render better patient care.